EPH Receptor B2 抗体 (Internal Region)
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Quick Overview for EPH Receptor B2 抗体 (Internal Region) (ABIN375195)
抗原
See all EPH Receptor B2 (EPHB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts to EPHB2.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. -
纯化方法
- ammonium sulphate precipitation followed by antigen affinity chromatography
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免疫原
- Peptide with sequence C-QKDRNHRPKFGQ, from the internal region of the protein sequence
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应用备注
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ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- EPH Receptor B2 (EPHB2)
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别名
- EPHB2
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背景
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: DRT, DRT, EPHT3, EPTH3, ERK, Ephrin type-B receptor 2, HEK5, NY-REN-47, Receptor protein-tyrosine kinase HEK5, Renal carcinoma antigen NY-REN-47, TYRO5, Tyrosine-protein kinase TYRO5, Tyrosine-protein kinase receptor EPH-3
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基因ID
- 2048
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NCBI登录号
- NP_004433
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UniProt
- P29323
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途径
- RTK signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
抗原
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