BDKRB1 抗体 (Internal Region)
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Quick Overview for BDKRB1 抗体 (Internal Region) (ABIN375179)
抗原
See all BDKRB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts to Bradykinin receptor B1.
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纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence KVWELYKQCTPK, from the internal region of the protein sequence
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anti-Bradykinin Receptor B1 (BDKRB1) (AA 161-260) antibody
BDKRB1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (Cytoplasmic Domain) antibodyBDKRB1 适用: 人 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (AA 1-353) antibodyBDKRB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A2 unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (Extracellular Domain) antibodyBDKRB1 适用: 人, 猴 IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (C-Term) antibodyBDKRB1 适用: 人, 猴 IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (AA 202-214), (Extracellular), (Loop 2) antibodyBDKRB1 适用: 小鼠 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (AA 1-353) antibodyBDKRB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (AA 1-353) antibodyBDKRB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (Internal Region) antibodyVerified BDKRB1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (AA 230-279) antibodyBDKRB1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/1000. Western Blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0,5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Genetic variation and gender determine bradykinin type 1 receptor responses in human tissue: implications for the ACE-inhibitor-induced effects in patients with coronary artery disease." in: Clinical science (London, England : 1979), Vol. 126, Issue 6, pp. 441-9, (2014) (PubMed).
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- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
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别名
- BDKRB1
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背景
- Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Bradykinin B1 receptor is generally only minimally expressed under normal physiological conditions, but the expression is induced rapidly under pathologic conditions such as ischemia, atheromatous disease, or exposure to inflammatory cytokines.Synonyms: B1 bradykinin receptor, B1R, BK-1 receptor, BKB1R, BKR1, BRADYB1, Bradykinin B1 Receptor
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基因ID
- 623
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NCBI登录号
- NP_000701
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UniProt
- P46663
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途径
- ACE Inhibitor Pathway
抗原
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