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AADAT 抗体 (Internal Region)

The 山羊 多克隆 anti-AADAT antibody (ABIN375162) specifically detects AADAT in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN375162
发货至: 中国
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Quick Overview for AADAT 抗体 (Internal Region) (ABIN375162)

抗原

See all AADAT 抗体
AADAT (Aminoadipate Aminotransferase (AADAT))

适用

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宿主

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山羊

克隆类型

  • 39
  • 1
多克隆

标记

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This AADAT antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Internal Region

    特异性

    This antibody reacts to AADAT.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-KPEDAKNPQKNTPK, from the internal region of the protein sequence
  • 应用备注

    Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    AADAT (Aminoadipate Aminotransferase (AADAT))

    别名

    AADAT

    背景

    Aminoadipate aminotransferase (AADAT) is a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. Kynurenine aminotransferase catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid. Kynurenic acid is an antagonist at the glycine site of NMDA receptors and increased levels of kynurenic acid are thought to exert a neuroprotective action in some pathological conditions.Synonyms: 2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, KAT2, Kynurenine aminotransferase II, Kynurenine-oxoglutarate aminotransferase II, Kynurenine-oxoglutarate transaminase II

    基因ID

    51166, 9606

    UniProt

    Q8N5Z0
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