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CST3 抗体 (Internal Region)

This 山羊 多克隆 antibody specifically detects CST3 in WB. It exhibits reactivity toward 人.
产品编号 ABIN375142
发货至: 中国
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Quick Overview for CST3 抗体 (Internal Region) (ABIN375142)

抗原

See all CST3 抗体
CST3 (Cystatin C (CST3))

适用

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  • 54
  • 45
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宿主

  • 98
  • 51
  • 10
  • 3
  • 3
山羊

克隆类型

  • 91
  • 74
多克隆

标记

  • 83
  • 17
  • 10
  • 4
  • 4
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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This CST3 antibody is un-conjugated

应用范围

  • 105
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  • 4
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  • 3
  • 1
  • 1
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  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 24
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
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    Internal Region

    序列

    C-SVEEEGVRRA LD

    特异性

    This antibodyrecognizes CST3 / cystatin C.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

    免疫原

    Peptide with sequence from the internal region of the protein sequence according to NP_000090.1. Genename: CST3
  • 应用备注

    Peptide ELISA: 1/8000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CST3 (Cystatin C (CST3))

    别名

    Cystatin-C

    背景

    Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. The cystatin superfamily encompasses proteins that contain multiple cystatin like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. Cystatin C (Cystatin 3) , a secreted molecule of this family, is of interest from biochemical, medicine and evolutionary points of view. Cystatin C, with molecular weight of 13260 Da, is composed of 120 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases, and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis and abdominal aortic aneurysm.Synonyms: CST3, Cystatin C, Cystatin-3, Gamma-trace, Neuroendocrine basic polypeptide, Post-gamma-globulin

    基因ID

    1471

    NCBI登录号

    NP_000090

    UniProt

    P01034
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