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Clusterin 抗体 (C-Term)

Name: Clusterin 抗体 (C-Term)
SKU: ABIN375042
Availability: OutOfStock

CLU 适用: 大鼠, 小鼠 WB, EIA 宿主: 山羊 Polyclonal unconjugated

Image no. 1 for anti-Clusterin (CLU) (C-Term) antibody (ABIN375042) (Clusterin 抗体 (C-Term))

1 image

(1 reference)

产品编号 ABIN375042

发货至: 中国

Datasheet as PDF

抗原 See all Clusterin (CLU) 抗体

Clusterin (CLU)
抗原表位
14

10

9

8

7

6

6

6

4

4

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
91

30

28

12

8

7

2

1

1

1
大鼠, 小鼠
宿主
88

36

7

6

2

1
山羊
Compatible Secondaries
克隆类型
102

36

1
多克隆
标记
79

26

18

4

3

3

1

1

1

1

1

1

1
This Clusterin antibody is un-conjugated
应用范围
114

69

59

24

23

20

17

12

8

6

6

3

3

2

1

1

1

1
Western Blotting (WB), Enzyme Immunoassay (EIA)

序列

C-EKALQEYRRK SRAE

特异性

This antibody recognizes Clusterin / ApoJ (C-term).

交叉反应（详细）

Species reactivity (tested):Mouse, Rat.

纯化方法

Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

免疫原

Peptide with sequence from the C Terminus of the protein sequence according to NP_038520.1. Genename: Clu

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anti-Clusterin (CLU) (AA 331-449) antibody
CLU 适用: 人, 大鼠, 小鼠 ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Clusterin (CLU) (AA 229-446) antibody
CLU 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Clusterin (CLU) (AA 227-448) antibody
CLU 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Clusterin (CLU) (AA 228-449) antibody
CLU 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Clusterin (CLU) (AA 226-447) antibody
CLU 适用: 兔 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D4 unconjugated

anti-Clusterin (CLU) (C-Term) antibody
Verified CLU 适用: 人 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Clusterin (CLU) (AA 23-120) antibody
CLU 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Clusterin (CLU) (AA 227-447) antibody
CLU 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated

anti-Clusterin (CLU) (AA 402-501) antibody
CLU 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A11 unconjugated

anti-Clusterin (CLU) (Internal Region) antibody
CLU 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Peptide ELISA: 1/8000. Western Blot: 0.3-1 μg/mL. Approx.37 kDa band observed in Mouse Brain and Testis lysatesand in Rat Brain and Ovary lysates (calculated MW of 51.7 kDa according to Mouse

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Charnay, Imhof, Vallet, Hakkoum, Lathuiliere, Poku, Aronow, Kovari, Bouras, Giannakopoulos: "Clusterin expression during fetal and postnatal CNS development in mouse." in: Neuroscience, Vol. 155, Issue 3, pp. 714-24, (2008) (PubMed).
抗原

Clusterin (CLU)

别名

Apolipoprotein J (Apo J) (CLU 产品)

别名

LOC100136120 antibody, clu antibody, MGC53055 antibody, zgc:73352 antibody, xclu antibody, MGC89163 antibody, CLU antibody, APO-J antibody, APOJ antibody, CLI antibody, CLU1 antibody, CLU2 antibody, KUB1 antibody, NA1/NA2 antibody, SGP-2 antibody, SGP2 antibody, SP-40 antibody, TRPM-2 antibody, TRPM2 antibody, DAG antibody, RATTRPM2B antibody, SP40 antibody, TRPM2B antibody, Trpm2 antibody, Trpmb antibody, AI893575 antibody, ApoJ antibody, Cli antibody, D14Ucla3 antibody, Sgp-2 antibody, Sgp2 antibody, Sugp-2 antibody, GP80 antibody, gpIII antibody, 40 antibody, clusterin-1 antibody, clusterin L homeolog antibody, clusterin antibody, Clusterin antibody, LOC100136120 antibody, clu.L antibody, clu antibody, CLU antibody, clus antibody, Clu antibody, LOC101113728 antibody

背景

At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individual's relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A-1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL). Apolipoprotein J is the major secreted product of Sertoli cells and is thought to play a critical role in spermatogenesis. The protein was shown to be a normal constituent of human blood and is also thought to be a control mechanism of the complement cascade. It prevents the binding of a C5b-C7 complex to the membrane of the target cell and in this way inhibits complement-mediated cytolysis. Apolipoprotein J is overexpressed in human prostate and breast cancers and in squamous cell carcinomas. Suppression of Apolipoprotein J renders these cells sensitive to chemotherapeutic drug-mediated apoptosis. It has been proposed that elevated levels of Apolipoprotein J may promote oncogenic transformation and tumor progression by interfering with BAX proapoptotic activities.Synonyms: 40, 40, AAG4, APOJ, Aging-associated gene 4 protein, CLI, Clusterin, Complement cytolysis inhibitor, Complement-associated protein SP-40, KUB1, Ku70-binding protein 1, NA1/NA2, SP-40, Testosterone-repressed prostate message 2

基因ID

12759, 10090

UniProt

Q06890

途径

Apoptosis, Negative Regulation of intrinsic apoptotic Signaling