AICDA 抗体 (N-Term)
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Quick Overview for AICDA 抗体 (N-Term) (ABIN374978)
抗原
See all AICDA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to AID.
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交叉反应 （详细）
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Species reactivity (expected):Pig, Cow.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence RRKFLYQFKNVR-C, from the N Terminus of the protein sequence
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anti-Activation-Induced Cytidine Deaminase (AICDA) (N-Term) antibody
AICDA 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (C-Term) antibodyAICDA 适用: 人, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (C-Term) antibodyAICDA 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (Internal Region) antibodyAICDA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (AA 1-198) antibodyAICDA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (N-Term) antibodyVerified AICDA 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (N-Term) antibodyAICDA 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (AA 1-60) antibodyAICDA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (AA 178-198) antibodyAICDA 适用: 人, 小鼠 WB, IF, IP 宿主: 大鼠 Monoclonal 328-8b unconjugated
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应用备注
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Peptide ELISA: 1/1000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0,5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- AICDA (Activation-Induced Cytidine Deaminase (AICDA))
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别名
- AICDA / AID
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背景
- AID or AICDA (activation-induced cytidine deaminase) is an RNA editing deaminase involved in somatic hypermutation, gene conversion, and class switch recombination. Expression of AID is restricted to stimulated B lymphocytes and it is required for several crucial steps of B cell terminal differentiation necessary for efficient antibody responses. It catalyses the deamination of Cytidine to uridine and ammonia and is strongly expressed in lymph nodes and tonsils. Defects in AICDA are the cause of autosomal recessive hyper IgM immunodeficiency syndrome type 2 (HIGM2) which is characterized by normal or elevated serum IgM levels with the absence of IgG, IgA, and IgE, resulting in a profound susceptibility to bacterial infections.Synonyms: Activation-induced cytidine deaminase, Cytidine aminohydrolase
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基因ID
- 57379, 9606
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UniProt
- Q9GZX7
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response
抗原
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