MANF 抗体 (Internal Region)
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Quick Overview for MANF 抗体 (Internal Region) (ABIN374894)
抗原
See all MANF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts to ARMET.
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence KFCREARGKENR, from the internal region of the protein sequence
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anti-Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) (AA 25-182) antibody
MANF 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) (AA 28-182) antibodyMANF 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) (AA 116-185) antibodyMANF 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) (C-Term) antibodyKO Validated MANF 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) (AA 25-182) antibodyMANF 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) antibodyMANF 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) antibodyMANF 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) (AA 1-182) antibodyMANF 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) (Internal Region) antibodyVerified MANF 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) (AA 132-182) antibodyMANF 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0,5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
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别名
- ARMET / ARP
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背景
- ARMET, also known as MANF, was initially identified as a protein containing an arginine-rich region that was highly mutated in a variety of tumors. More recently it was identified as a mesencephalic astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons, similar to glial cell line-derived neurotrophic factor (GDNF) and CDNF. In rat brain slices, ARMET enhanced nigral gamma-aminobutyric acid release. Like GDNF and CDNF, ARMET has selective neuroprotective activity for dopaminergic neurons suggesting that it may be indicated for the treatment of Parkinson's disease. Expression of ARMET has also been shown to be induced during ER stress, suggesting that it may play a role in protein quality control during ER stress.Synonyms: Arginine-rich protein, MANF, Mesencephalic astrocyte-derived neurotrophic factor
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基因ID
- 7873, 9606
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UniProt
- P55145
抗原
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