电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

MANF 抗体 (Internal Region)

MANF 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374894
发货至: 中国
  • 抗原 See all MANF 抗体
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    抗原表位
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 47
    • 20
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 38
    • 8
    • 1
    山羊
    克隆类型
    • 41
    • 6
    多克隆
    标记
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MANF antibody is un-conjugated
    应用范围
    • 39
    • 24
    • 10
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to ARMET.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence KFCREARGKENR, from the internal region of the protein sequence
    Top Product
    Discover our top product MANF Primary Antibody
  • 应用备注
    Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0,5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    别名
    ARMET / ARP (MANF 产品)
    别名
    ARMET antibody, ARP antibody, 3230402M22Rik antibody, AA407711 antibody, AA408789 antibody, AA673178 antibody, Armet antibody, D17914 antibody, D18Mgi17 antibody, MANF antibody, RBM15B antibody, ARP-like antibody, CG7013 antibody, DmMANF antibody, Dmel\\CG7013 antibody, anon-EST:ParkEST188 antibody, arp antibody, armet antibody, im:6909481 antibody, zgc:153327 antibody, manf antibody, mesencephalic astrocyte derived neurotrophic factor antibody, mesencephalic astrocyte-derived neurotrophic factor antibody, RNA binding motif protein 15B antibody, Mesencephalic astrocyte-derived neurotrophic factor antibody, mesencephalic astrocyte-derived neurotrophic factor S homeolog antibody, MANF antibody, Manf antibody, RBM15B antibody, manf antibody, manf.S antibody
    背景
    ARMET, also known as MANF, was initially identified as a protein containing an arginine-rich region that was highly mutated in a variety of tumors. More recently it was identified as a mesencephalic astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons, similar to glial cell line-derived neurotrophic factor (GDNF) and CDNF. In rat brain slices, ARMET enhanced nigral gamma-aminobutyric acid release. Like GDNF and CDNF, ARMET has selective neuroprotective activity for dopaminergic neurons suggesting that it may be indicated for the treatment of Parkinson's disease. Expression of ARMET has also been shown to be induced during ER stress, suggesting that it may play a role in protein quality control during ER stress.Synonyms: Arginine-rich protein, MANF, Mesencephalic astrocyte-derived neurotrophic factor
    基因ID
    7873, 9606
    UniProt
    P55145
You are here:
客服