VANGL2 抗体 (Internal Region)
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Quick Overview for VANGL2 抗体 (Internal Region) (ABIN374805)
抗原
See all VANGL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-QKYLRTTKQQ PYH
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特异性
- This antibody detects Vang-like protein 2 (VANGL2).
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交叉反应 (详细)
- Species reactivity (expected):Cow, ZebrafishSpecies reactivity (tested):Human, Mouse
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from the internal region of the protein sequence according to NP_065068.1 Genename: VANGL2
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应用备注
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Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.3-1 μg/mL. Approx 55 kDa band observed in Human Lung and Mouse Brainlysates (calculated MW of 59.5 kDa according to NP_065068.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- VANGL2 (Vang-Like 2 (VANGL2))
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别名
- Vang-Like Protein 2 (VANGL2)
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背景
- VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.Synonyms: KIAA1215, Loop-tail protein 1 homolog, STB1, Strabismus 1, Van Gogh-like protein 2
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基因ID
- 57216, 9606
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UniProt
- Q9ULK5
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途径
- WNT signaling, Stem Cell Maintenance, Tube Formation, Asymmetric Protein Localization
抗原
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