ALOX5AP 抗体 (Internal Region)
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北京 101111
Quick Overview for ALOX5AP 抗体 (Internal Region) (ABIN374740)
抗原
See all ALOX5AP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-HKVEHESRTQ NGR
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特异性
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This antibody recognizes ALOX5AP / FLAP.
Cellular Localization: Nucleus membrane. Endoplasmic reticulum membrane. -
交叉反应 （详细）
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Species reactivity (expected):Canine.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_001620.2.
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anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (C-Term) antibody
Verified ALOX5AP 适用: 人 ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (Internal Region) antibodyVerified ALOX5AP 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) antibodyALOX5AP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3940 unconjugated Recombinant Antibody
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (AA 86-117) antibodyALOX5AP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17169 unconjugated
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (Internal Region) antibody (Biotin)Verified ALOX5AP 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal Biotin
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (Internal Region) antibodyALOX5AP 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) antibodyALOX5AP 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (AA 94-124) antibodyALOX5AP 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
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别名
- ALOX5AP / FLAP
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背景
- Genetic variations in ALOX5AP may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. Note=Genetic variations in ALOX5AP may be associated with susceptibility to myocardial infarction. Involvement in myocardial infarction is however unclear: according to some authors (PubMed:14770184), a 4-SNP haplotype in ALOX5AP confers risk of myocardial infarction, while according to other (PubMed:17304054) ALOX5AP is not implicated in this condition. Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.Synonyms: Arachidonate 5-lipoxygenase-activating protein, MK-886-binding protein
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基因ID
- 241, 9606
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UniProt
- P20292
抗原
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