CPT1A 抗体 (Internal Region)
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Quick Overview for CPT1A 抗体 (Internal Region) (ABIN374737)
抗原
See all CPT1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts to CPT1A. But is not expected to recognise CPT1B.
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纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence C-DPAQTVEQRLKLFK, from the internal region of the protein sequence
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anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 191-353) antibody
CPT1A 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (Middle Region) antibodyCPT1A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (Internal Region) antibodyVerified CPT1A 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 301-600) antibodyCPT1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 1-100) antibodyCPT1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 461-550) antibodyCPT1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 606-636), (C-Term) antibodyCPT1A 适用: 人, Cow WB, IHC (p) 宿主: 兔 Polyclonal RB4655 unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 572-773) antibodyCPT1A 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 606-636) antibodyCPT1A 适用: 人, Cow WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 568-773) antibodyCPT1A 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL. Immunohistochemistryon paraffin sections: 4 - 6 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation." in: Nature communications, Vol. 6, pp. 6692, (2015) (PubMed).
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- CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
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别名
- CPT1A / CPT1-L
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背景
- Carnitine palmitoyltransferase 1A (CPT1A) is involved in the mitochondrial oxidation of long chain fatty acids. The oxidation of long chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine acylcarnitine translocase. CPT I is the key enzyme in the carnitine dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta oxidation.Synonyms: Carnitine O-palmitoyltransferase 1 liver isoform, Carnitine palmitoyltransferase 1A
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基因ID
- 1374, 9606
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UniProt
- P50416
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途径
- AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
抗原
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