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Serotonin Receptor 3A 抗体 (Internal Region)

This 山羊 多克隆 antibody specifically detects Serotonin Receptor 3A in WB, IF 和 EIA. It exhibits reactivity toward 人 和 大鼠. It has been mentioned in 2+ publications
产品编号 ABIN374713
发货至: 中国
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Quick Overview for Serotonin Receptor 3A 抗体 (Internal Region) (ABIN374713)

抗原

See all Serotonin Receptor 3A (HTR3A) 抗体
Serotonin Receptor 3A (HTR3A)

适用

  • 61
  • 17
  • 13
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 61
  • 2
  • 2
  • 1
山羊

克隆类型

  • 63
  • 3
多克隆

标记

  • 29
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Serotonin Receptor 3A antibody is un-conjugated

应用范围

  • 30
  • 23
  • 14
  • 14
  • 11
  • 5
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  • 4
  • 3
  • 2
  • 1
  • 1
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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 8
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
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    Internal Region

    序列

    C-GPQDFEKSPR DR

    特异性

    This antibody is expected to recognize all three reported isoforms (NP_998786.2, NP_000860.2, NP_001155244.1).

    交叉反应 (详细)

    Species reactivity (tested):Human, Rat.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide with sequence from the internal region of the protein sequence Genename: HTR3A
  • 应用备注

    ELISA: 1/128000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • do Amaral, Ueno, Oliveira, Borsonello, Vanzela, Ribeiro, Alves, Barbosa, Carneiro, Boschero: "Reduced expression of SIRT1 is associated with diminished glucose-induced insulin secretion in islets from calorie-restricted rats." in: The Journal of nutritional biochemistry, Vol. 22, Issue 6, pp. 554-9, (2011) (PubMed).

    Lu, Hsieh, Dun, Oprea, Wang, Luo, Lin, Chang, Lee: "Estrogen rapidly modulates 5-hydroxytrytophan-induced visceral hypersensitivity via GPR30 in rats." in: Gastroenterology, Vol. 137, Issue 3, pp. 1040-50, (2009) (PubMed).

  • 抗原

    Serotonin Receptor 3A (HTR3A)

    背景

    5-hydroxytryptamine (serotonin) receptors is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The 5HT3A receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.Synonyms: 5-HT3A, 5-HT3R, 5-hydroxytryptamine receptor 3A, Serotonin-gated ion channel receptor

    基因ID

    3359

    NCBI登录号

    NP_000860

    UniProt

    P46098

    途径

    Synaptic Membrane
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