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PDE4D 抗体 (C-Term)

This 山羊 多克隆 antibody specifically detects PDE4D in WB 和 EIA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN374635
发货至: 中国
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Quick Overview for PDE4D 抗体 (C-Term) (ABIN374635)

抗原

See all PDE4D 抗体
PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

适用

  • 54
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  • 2
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  • 1
  • 1
人, 小鼠

宿主

  • 56
  • 1
  • 1
山羊

克隆类型

  • 54
  • 4
多克隆

标记

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  • 5
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
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This PDE4D antibody is un-conjugated

应用范围

  • 50
  • 21
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  • 16
  • 11
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  • 6
  • 5
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 16
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    C-Term

    序列

    QPEACVIDDR SPDT

    特异性

    This antibody detects PDE4D at C-term and is expected to recognize all reported isoforms.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide with sequence from the C-Terminus of the protein sequence according to NP_001098101.1, NP_006194.2, NP_001159371.1. Genename: PDE4D
  • 应用备注

    Peptide ELISA: 1/128000. Western Blot. : 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

    别名

    PDE4D

    背景

    Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'- monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE4 enzyme belongs to a family of cAMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger, cAMP. Four genes (4A, 4B, 4C, and 4D) encode around 20 distinct isoform members of the PDE4 family. Each isoform is characterized by a unique N-terminal region.Synonyms: 5'-cyclic phosphodiesterase 4D, DPDE3, EC=3.1.4.17, PDE43, PDE4D, cAMP-specific 3'

    基因ID

    5144

    NCBI登录号

    NP_001098101

    UniProt

    Q08499

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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