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MMP7 抗体 (C-Term)

The 山羊 多克隆 anti-MMP7 antibody is suitable to detect MMP7 in samples from 人. It has been validated for WB, IHC (p) 和 EIA.
产品编号 ABIN374597
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MMP7 抗体 (C-Term) (ABIN374597)

抗原

See all MMP7 抗体
MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This MMP7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    序列

    C-QKLYGKRSNS RKK

    特异性

    This antibody recognizes MMP-7 at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide with sequence from the C Terminus of the protein sequence according to NP_002414.1. Genename: MMP7
  • 应用备注

    Peptide ELISA: 1/64000. Western Blot: 0.03 - 0.1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

    别名

    MMP-7

    背景

    Matrix Metalloproteinases (MMPs) belong to a family of proteases that are essential for the breakdown of extracellular matrix (ECM). They are thus important in apoptosis, tumor cell growth, invasion, and metastasis, as well as angiogenesis and wound healing. Most MMPs contain common domain structures that include a signal sequence, a propeptide, a catalytic domain, and a hemopexin like (Hpx) domain. MMP7, also known as Matrilysin, is responsible for hydrolyzing proteoglycans and ECM glycoproteins. It is expressed in normal cells, specifically glandular epithelial cells. MMP7, is thought to play an important role in the early steps of tumor progression. Expression of MMP2, MMP7 and MMP11 is greater in pancreatic carcinoma than in normal pancreas.Synonyms: MMP7, MPSL1, Matrilysin, Matrin, Matrix metalloproteinase-7, PUMP1, Pump-1 protease, Uterine metalloproteinase

    基因ID

    4316, 9606

    UniProt

    P09237

    途径

    Production of Molecular Mediator of Immune Response
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