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PPY 抗体 (Internal Region)

PPY 适用: 人, 大鼠, 小鼠, 犬 WB, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374577
发货至: 中国
  • 抗原 See all PPY 抗体
    PPY (Pancreatic Polypeptide (PPY))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    人, 大鼠, 小鼠, 犬
    宿主
    • 17
    • 4
    • 2
    山羊
    克隆类型
    • 19
    • 4
    多克隆
    标记
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPY antibody is un-conjugated
    应用范围
    • 13
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    序列
    C-TRPRYGKRHK EDT
    特异性
    This antibody recognizes Pancreatic prohormone.
    交叉反应 (详细)
    Species reactivity (expected):Rat and Canine (Dog).
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Synthetic peptide from the internal region of the protein sequence according to NP_002713.1. Genename: PPY
    Top Product
    Discover our top product PPY Primary Antibody
  • 应用备注
    Peptide ELISA: Antibody Detection Limit Dilution: 1/32000. Western Blot: Preliminary experiments gave an approx 35-38 kDa band in human pancreaslysates after 1 μg/mL antibody staining. Please note that currently we cannot find anexplanation in the literature for the band we observe given the calculated size of 10.8 kDaaccording to NP_002713.1. The 38 kDa band was successfully blocked by incubation withthe immunizing peptide. Immunohistochemistry: 3 μg/mL. In paraffin embedded human pancreas, shows strong cytoplasmic staining of rare cellslocated at the periphery of islets of Langerhans.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PPY (Pancreatic Polypeptide (PPY))
    别名
    Pancreatic Prohormone (PPY 产品)
    别名
    PPY antibody, PNP antibody, PP antibody, AV061413 antibody, IGSPP antibody, pancreatic polypeptide antibody, peptide YY antibody, PPY antibody, Ppy antibody, PYY antibody
    背景
    Pancreatic hormone (PPY) is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma levels of this hormone have been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.Synonyms: Obinepitide, PNP, PPY, Pancreatic polypeptide
    基因ID
    5539
    NCBI登录号
    NP_002713
    UniProt
    P01298
    途径
    Feeding Behaviour
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