Arrestin 3 抗体 (Internal Region)
(3 references)Quick Overview for Arrestin 3 抗体 (Internal Region) (ABIN374557)
抗原
See all Arrestin 3 (ARRB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-HDHIPLPRPQ S
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特异性
- This antibody is expected to recognizse both reported isoforms NP_004304.1 and NP_945355.1. No cross-reactivity is expected with Arrestin beta 1.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_004304.1, NP_945355.1. Genename: ARRB2
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anti-Arrestin, beta 2 (ARRB2) (Internal Region) antibody
Verified ARRB2 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-409) antibodyARRB2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-400) antibodyARRB2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-409) antibodyARRB2 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 222-369) antibodyARRB2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (C-Term) antibodyARRB2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (Middle Region) antibodyARRB2 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (Middle Region) antibodyARRB2 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 251-418) antibodyARRB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 262-430) antibodyARRB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Urinary biomarkers of chronic allograft nephropathy." in: Proteomics. Clinical applications, Vol. 9, Issue 5-6, pp. 574-85, (2015) (PubMed).
: "Generation of induced pluripotent stem cells from human renal proximal tubular cells with only two transcription factors, OCT4 and SOX2." in: The Journal of biological chemistry, Vol. 287, Issue 29, pp. 24131-8, (2012) (PubMed).
: "Reduced expression of arrestin beta 2 by graft monocytes during acute rejection of rat kidneys." in: Immunobiology, Vol. 216, Issue 7, pp. 854-61, (2011) (PubMed).
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: "Urinary biomarkers of chronic allograft nephropathy." in: Proteomics. Clinical applications, Vol. 9, Issue 5-6, pp. 574-85, (2015) (PubMed).
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- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
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别名
- Arrestin beta-2 / ARRB2
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背景
- Members of arrestin/beta arrestin protein family are thought to participate in agonist mediated desensitization of G protein coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors.Synonyms: ARB2, ARR2, Beta-arrestin-2
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分子量
- 46.1 kDa according to NP_004304.1 and 44.4 according to NP_945355.1.
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基因ID
- 409, 9606
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UniProt
- P32121
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
抗原
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