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HNF4A 抗体 (N-Term)

The 山羊 多克隆 anti-HNF4A antibody (ABIN374541) specifically detects HNF4A in WB. The antibody is reactive with 人 samples.
产品编号 ABIN374541
发货至: 中国
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Quick Overview for HNF4A 抗体 (N-Term) (ABIN374541)

抗原

See all HNF4A 抗体
HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This HNF4A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    This antibody reacts to HNF-4-alpha. This antibody is expected to recognise the reported isoforms a, b and c.

    交叉反应 (详细)

    Species reactivity (expected):Canine, Porcine.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence RLSKTLVDMDMADY-C, from the N Terminus of the protein sequence
  • 应用备注

    Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

    别名

    HNF4 alpha / TCF14

    背景

    The protein encoded by the HNF4 gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin dependent diabetes mellitus type I. At least three different transcript variants encoding three different isoforms have been found for this gene.Synonyms: HNF4, HNF4A, Hepatocyte nuclear factor 4-alpha, NR2A1, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, Transcription factor HNF-4

    基因ID

    3172

    NCBI登录号

    NP_000448

    UniProt

    P41235

    途径

    AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process
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