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FTCD 抗体 (Internal Region)

The 山羊 多克隆 anti-FTCD antibody (ABIN374454) specifically detects FTCD in WB, IHC (p) 和 EIA. The antibody is reactive with 人, 小鼠, 大鼠 和 Pig samples.
产品编号 ABIN374454
发货至: 中国
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Quick Overview for FTCD 抗体 (Internal Region) (ABIN374454)

抗原

See all FTCD 抗体
FTCD (Formiminotransferase Cyclodeaminase (FTCD))

适用

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人, 小鼠, 大鼠, Pig

宿主

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山羊

克隆类型

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多克隆

标记

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This FTCD antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Internal Region

    序列

    CLREQGRGKD QPGRL

    特异性

    This antibody recognizes 58KGolgi protein (Internal).

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat and Pig.
    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide from the internal region of the protein sequence according to NP_006648.1, NP_996848.1 Genename: FTCD
  • 应用备注

    Peptide ELISA: Antibody Detection Limit: 1/64000. Western blot: 0.01-0.03 μg/mL. Detects a approx. 60 kDa band in Human Liver lysates (calculatedMW of 58.0 kDa according to NP_006648.1 and NP_996848.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FTCD (Formiminotransferase Cyclodeaminase (FTCD))

    别名

    58K Golgi Protein

    背景

    58K Golgi protein antibodies are excellent for use as markers for the Golgi complex. The 58K Golgi protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency, also known as formiminoglutamicaciduria (FIGLU-uria). It is an autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.Synonyms: FTCD, Formimidoyltransferase-cyclodeaminase, Formiminotransferase-cyclodeaminase, Golgi Marker 58K, Golgi marker, LCHC1

    基因ID

    10841, 9606

    UniProt

    O95954
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