FTCD 抗体 (N-Term)
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Quick Overview for FTCD 抗体 (N-Term) (ABIN374453)
抗原
See all FTCD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SQLVECVPNF SEGKNQ
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特异性
- This antibody recognizes 58K Golgi protein at N-term.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Pig.
Species reactivity (tested):Human. -
纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from the N-Terminus of the protein sequence according to NP_006648.1, NP_996848.1. Genename: FTCD
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anti-Formiminotransferase Cyclodeaminase (FTCD) (Internal Region) antibody
Verified FTCD 适用: 人, 小鼠, Pig WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Formiminotransferase Cyclodeaminase (FTCD) (N-Term) antibodyVerified FTCD 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Formiminotransferase Cyclodeaminase (FTCD) antibodyFTCD 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4A7 unconjugated
anti-Formiminotransferase Cyclodeaminase (FTCD) (N-Term) antibodyFTCD 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow, 兔, 猴, 豚鼠, 马, Hamster, 小鸡, Cat, Avian, 驴, 山羊, 绵羊 WB, IHC (p), IF, IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Formiminotransferase Cyclodeaminase (FTCD) (AA 440-541) antibodyFTCD 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3A4 unconjugated
anti-Formiminotransferase Cyclodeaminase (FTCD) antibodyFTCD 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-Formiminotransferase Cyclodeaminase (FTCD) (N-Term) antibodyFTCD 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Formiminotransferase Cyclodeaminase (FTCD) antibodyFTCD 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8C2 unconjugated
anti-Formiminotransferase Cyclodeaminase (FTCD) (AA 412-541) antibodyFTCD 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Formiminotransferase Cyclodeaminase (FTCD) antibodyFTCD 适用: 人, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 7C5 unconjugated
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应用备注
- Peptide ELISA: Detection Limit: 1/64000. Western blot: 0.03-0.5 μg/mL. Detects a 55-60 kDa band in Human Liver lysate (PredictedMolecular Weight: 58.0 kDa). Immunohistochemistry: 3-5 μg/mL. In paraffin embedded Human Liver shows distinct staining of membranes and cytoplasm ina selection of hepatocytes.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FTCD (Formiminotransferase Cyclodeaminase (FTCD))
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别名
- 58K Golgi Protein
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背景
- 58K Golgi protein antibodies are excellent for use as markers for the Golgi complex. The 58K Golgi protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency, also known as formiminoglutamicaciduria (FIGLU-uria). It is an autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.Synonyms: FTCD, Formimidoyltransferase-cyclodeaminase, Formiminotransferase-cyclodeaminase, Golgi Marker 58K, Golgi marker, LCHC1
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基因ID
- 10841, 9606
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UniProt
- O95954
抗原
-
