LAT 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for LAT 抗体 (C-Term) (ABIN374446)
抗原
See all LAT 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- C-GAPDYENLQE LN
-
特异性
- This antibody is expected to recognize isoform a (NP_055202.1), isoform b (NP_001014987.1 and NP_001014989.1) and isoform c (NP_001014988.1).
-
交叉反应 （详细）
- Species reactivity (tested):Human, Mouse and Rat.
-
纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
-
免疫原
- Peptide from the C Terminus of the protein sequence according to NP_055202.1, NP_001014987.1, NP_001014989.1, NP_001014988.1
-
-
anti-Linker For Activation of T Cells (LAT) (Cytoplasmic Domain) antibody
LAT 适用: 人 WB, IP, ICFC 宿主: 小鼠 Monoclonal LAT-01 unconjugated
anti-Linker For Activation of T Cells (LAT) antibodyLAT 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (pTyr191) antibodyLAT 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Monoclonal 2E4 unconjugated Recombinant Antibody
anti-Linker For Activation of T Cells (LAT) antibodyKD Validated LAT 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4940 unconjugated Recombinant Antibody
anti-Linker For Activation of T Cells (LAT) (AA 1-233) antibodyLAT 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B11-1D5 unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 30-237) antibodyLAT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (pTyr161) antibodyLAT 适用: 人 ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (Cytoplasmic Domain) antibodyLAT 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal LAT1111 unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 25-221) antibodyLAT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 33-227) antibodyLAT 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Peptide ELISA: 1/2,000. Western Blot: 1-3 μg/mL. Detects a band of Approx 35 kDa in Human PBMC lysates(Predicted Molecular Weight: 35 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store the antibody (in aliquots) at -20 °C.
-
-
- LAT (Linker For Activation of T Cells (LAT))
-
别名
- LAT
-
背景
- Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells.Synonyms: 36 kDa Phospho-Tyrosine Adapter Protein, Linker For Activation of T-Cells Family Member 1, p36-38, pp36
-
分子量
- 27.9kDa (NP_055202.1).
-
基因ID
- 27040
-
NCBI登录号
- NP_001014987
-
UniProt
- O43561
-
途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
抗原
-
