CPEB1 抗体 (C-Term)
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Quick Overview for CPEB1 抗体 (C-Term) (ABIN374439)
抗原
See all CPEB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-PLMRNQKNRD SS
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特异性
- This antibody recognizes CPEB1.
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交叉反应 （详细）
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Species reactivity (expected):Macaque.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide from the C Terminus of the protein sequence according to NP_085097.
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anti-Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) (AA 1-486) antibody
CPEB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) (AA 311-561) antibodyCPEB1 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) antibodyCPEB1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3495 unconjugated Recombinant Antibody
anti-Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) (C-Term) antibodyVerified CPEB1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) (Internal Region) antibodyCPEB1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) (AA 1-486) antibodyCPEB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) (C-Term) antibodyCPEB1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/128000. Western Blot: 0.5-2.0 μg/mL. Approx 65-70 kDa band observed in Human Brain lysates(predicted MW of 60 kDa according to NP_085097). Please note this band was always accompanied by a slightly stonger band at approx 40 kDaand further both bands could be blocked by incubation with the immunising peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
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别名
- CPEB1
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背景
- The regulated translation of messenger RNA is essential for cell cycle progression, establishment of the body plan during early development, and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, which is one mechanism of controlling translation, is driven by CPEB1 (Cytoplasmic Polyadenylation Element Binding protein), a highly conserved, sequence specific RNA binding protein that binds to the cytoplasmic polyadenylation element (CPE) and modulates translational repression and mRNA localisation. CPEB1 can assemble bothe translational activation and repression complexes via its binding to the CPE. In both vertebrates and invertebrates, the expression of several maternal mRNAs is regulated by cytoplasmic polyadenylation. In Xenopus oocytes, where most of the biochemical details of this process have been examined, polyadenylation is controlled by CPEB1.Synonyms: CPE-BP1, CPE-binding protein 1, Cytoplasmic polyadenylation element-binding protein 1, h-CEBP, hCPEB-1
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基因ID
- 64506
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NCBI登录号
- NP_001073001
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UniProt
- Q9BZB8
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途径
- Synaptic Membrane
抗原
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