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FOXC1 抗体 (C-Term)

Name: FOXC1 抗体 (C-Term)
SKU: ABIN374336
Availability: OutOfStock

FOXC1 适用: 人, 小鼠, 斑马鱼 WB, IHC (p), ChIP, EIA 宿主: 山羊 Polyclonal unconjugated

Image no. 2 for anti-Forkhead Box C1 (FOXC1) (C-Term) antibody (ABIN374336) (FOXC1 抗体 (C-Term))

Image no. 1 for anti-Forkhead Box C1 (FOXC1) (C-Term) antibody (ABIN374336) (FOXC1 抗体 (C-Term))

2 images

(3 references)

产品编号 ABIN374336

发货至: 中国

Datasheet as PDF

抗原 See all FOXC1 抗体

FOXC1 (Forkhead Box C1 (FOXC1))
抗原表位
11

8

5

3

3

2

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
54

33

19

4

2

2

1

1

1

1

1
人, 小鼠, 斑马鱼
宿主
55

2

1
山羊
Compatible Secondaries
克隆类型
57

1
多克隆
标记
28

7

4

3

2

2

2

2

2

2

2

2
This FOXC1 antibody is un-conjugated
应用范围
39

26

8

7

4

4

3

3

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP), Enzyme Immunoassay (EIA)

序列

RTSGAFVYDC SKF

特异性

This antibody detects FOXC1 / FKHL7 / FREAC3 at C-term.

交叉反应（详细）

Species reactivity (tested):Human, Mouse, Zebrafish.

纯化方法

Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

免疫原

Peptide from C-Terminus of the protein sequence according to NP_001444.2. Genename: FOXC1

Top Product

Discover our top product FOXC1 Primary Antibody
anti-Forkhead Box C1 (FOXC1) (C-Term) antibody
Verified FOXC1 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Forkhead Box C1 (FOXC1) antibody
FOXC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box C1 (FOXC1) (AA 1-79) antibody
FOXC1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box C1 (FOXC1) (Center) antibody
FOXC1 适用: 人, 小鼠, 大鼠, 小鸡 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box C1 (FOXC1) (AA 101-200) antibody
FOXC1 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box C1 (FOXC1) (AA 62-186) antibody
FOXC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box C1 (FOXC1) antibody
FOXC1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box C1 (FOXC1) (C-Term) antibody
FOXC1 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box C1 (FOXC1) (AA 464-553) antibody
FOXC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D11 unconjugated

anti-Forkhead Box C1 (FOXC1) (AA 406-455) antibody
FOXC1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-1.5 μg/mL. Approx 55 kDa band observed in Human Bone Marrow lysates(calculated MW of 56.5 kDa according to NP_001444.1). Immunohistochemistry: 3 μg/mL. In paraffin embedded Human Kidney shows nuclearstaining of some cells in the glomeruli.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
Doucette, Footz, Walter: "FOXC1 Regulates Expression of Prostaglandin Receptors Leading to an Attenuated Response to Latanoprost." in: Investigative ophthalmology & visual science, Vol. 59, Issue 6, pp. 2548-2554, (2019) (PubMed).

Fatima, Wang, Uchida, Norden, Liu, Culver, Dietz, Culver, Millay, Mukouyama, Kume: "Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation." in: The Journal of clinical investigation, Vol. 126, Issue 7, pp. 2437-51, (2017) (PubMed).

Ito, Goping, Berry, Walter: "Dysfunction of the stress-responsive FOXC1 transcription factor contributes to the earlier-onset glaucoma observed in Axenfeld-Rieger syndrome patients." in: Cell death & disease, Vol. 5, pp. e1069, (2014) (PubMed).
抗原

FOXC1 (Forkhead Box C1 (FOXC1))

别名

FOXC1 / FKHL7 / FREAC3 (FOXC1 产品)

别名

ARA antibody, FKHL7 antibody, FREAC-3 antibody, FREAC3 antibody, IGDA antibody, IHG1 antibody, IRID1 antibody, RIEG3 antibody, FoxC1 antibody, fkhl7 antibody, freac-3 antibody, freac3 antibody, igda antibody, ihg1 antibody, irid1 antibody, rieg3 antibody, xfd-11 antibody, ara antibody, FOXC1 antibody, foxc1 antibody, Fkh1 antibody, Mf1 antibody, Mf4 antibody, ch antibody, fkh-1 antibody, frkhda antibody, CFKH-1 antibody, XFD-11 antibody, foxc1.2 antibody, id:ibd5079 antibody, forkhead box C1 antibody, forkhead box C1 S homeolog antibody, forkhead box C1 L homeolog antibody, Forkhead box protein C1 antibody, winged helix transcription factor XFD-11 antibody, forkhead box C1b antibody, FOXC1 antibody, Foxc1 antibody, foxc1.S antibody, foxc1 antibody, foxc1.L antibody, foxc1-A antibody, foxc1b antibody

背景

FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined, however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.Synonyms: FREAC-3, Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3

分子量

56.8kDa (NP_001444.1).

基因ID

2296

NCBI登录号

NP_001444

UniProt

Q12948

途径

Chromatin Binding, Glycosaminoglycan Metabolic Process