CDT1 抗体 (C-Term)
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Quick Overview for CDT1 抗体 (C-Term) (ABIN374262)
抗原
See all CDT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-ARLAHQTRAE EGL
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特异性
- This antibody detects CDT1 at C-term.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from C Terminus of the protein sequence according to NP_112190.2. Genename: CDT1
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anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) antibody
KD Validated CDT1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5790 unconjugated Recombinant Antibody
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) antibodyCDT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (C-Term) antibodyVerified CDT1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (C-Term) antibodyCDT1 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 兔, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (C-Term) antibodyCDT1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (C-Term) antibodyCDT1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (AA 12-170) antibodyCDT1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (AA 400-449) antibodyCDT1 适用: 人, 小鼠, 大鼠, Pig, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (C-Term) antibodyCDT1 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Limit dilution 1: 64000. Western Blot: 1-3 μg/mL. Approx 65 kDa band observed in Human Brain lysates (predictedMW of 65 kDa according to NP_112190.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))
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别名
- CDT1
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背景
- Cdt1 and its inhibitor Geminin are important regulators of replication licensing. A critical balance between both proteins functions to ensure that each origin only fires once during the cell cycle. Cdt1 cooperates with Cdc6 to promote the loading of the MCM complex onto chromatin to form the pre-replication complex. Overexpression of Cdt1 leads to aberrant replication and activation of DNA damage checkpoints. It is also associated with a predisposition for malignant transformation.Synonyms: DNA replication factor Cdt1, DUB, Double parked homolog, RIS2
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基因ID
- 81620
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NCBI登录号
- NP_112190
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UniProt
- Q9H211
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途径
- MAPK Pathway, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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