MAP4K1 抗体 (N-Term)
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Quick Overview for MAP4K1 抗体 (N-Term) (ABIN374224)
抗原
See all MAP4K1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DVVDPDIFNR DPR-C
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特异性
- This antibody is expected to recognise isoform 1 (NP_001036065.1) and isoform 2 (NP_009112.1).
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Pig, Canine (Dog), Cow.
Species reactivity (tested):Human. -
纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from N Terminus of the protein sequence according to NP_001036065.1, NP_009112.1. Genename: MAP4K1
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应用备注
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Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-2 μg/mL. Approx 95-100 kDa band observed in Jurkat (predicted MW of90 kDa according to NP_009112).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
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- MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))
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别名
- MAP4K1
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背景
- MAP4K1 or HPKI (hematopoietic progenitor kinase I) is one of these mammalian kinases that have significant sequence similarity to the Saccharomyces Cerevisiae serine/threonine kinase STE20, which relays signals from G protein coupled receptors to cytosolic MAP kinase cascades. MAP4K1 may play a role in the response to environmental stress. It appears to act upstream of the JUN N terminal pathway. It may play a role in hematopoietic lineage decisions and growth regulation.Synonyms: HPK1, Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MEKKK 1, Mitogen-activated protein kinase kinase kinase kinase 1
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基因ID
- 11184
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NCBI登录号
- NP_001036065
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UniProt
- Q92918
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途径
- TCR Signaling, Signaling of Hepatocyte Growth Factor Receptor
抗原
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