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ADAM8 抗体 (C-Term)

The 山羊 多克隆 anti-ADAM8 antibody is suitable to detect ADAM8 in samples from 人. It has been validated for WB 和 EIA.
产品编号 ABIN374195
发货至: 中国
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Quick Overview for ADAM8 抗体 (C-Term) (ABIN374195)

抗原

See all ADAM8 抗体
ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This ADAM8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
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    C-Term

    序列

    C-QRKQGAGAPT AP

    特异性

    This antibody is expected to recognise isoform 1 and 3 (NP_001100.3 and NP_001157962.1).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide from C Terminus of the protein sequence according to NP_001100.3, NP_001157962.1. Genename: ADAM8
  • 应用备注

    Peptide ELISA: Limit dilution 1: 1000. Western blot: 1-3 μg/mL. Approx 90 kDa band seen in Human Brain lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

    别名

    CD156a / ADAM8

    背景

    Members of ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. The extracellular region of ADAM8 shows significant amino acid sequence homology to hemorrhagic snake venom proteins, including the metalloprotease and disintegrin domains. The expression of ADAM8 is upregulated by retinoic acid and vitamin D3. The function of ADAM8 is still poorly understood. ADAM8 has been shown to stimulate osteoclasts, and to be produced by bone marrow cultures stimulated by vitamin-D. ADAM8 is involved in protein processing at the cell surface and is also thought to act as a leukocyte differentiation marker.Synonyms: Cell surface antigen MS2, Disintegrin and metalloproteinase domain-containing protein 8, MS2

    分子量

    88.8 kDa according to NP_001100.3.

    基因ID

    101

    NCBI登录号

    NP_001100

    UniProt

    P78325

    途径

    Activation of Innate immune Response, M Phase
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