DKK2 抗体 (C-Term)
Quick Overview for DKK2 抗体 (C-Term) (ABIN374181)
抗原
See all DKK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects Dickkopf-2 at C-term.
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence ATYSSKARLHVCQKI, from the C Terminus of the protein sequence Genename: DKK2
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anti-Dickkopf 2 Homolog (DKK2) (AA 34-259) antibody
DKK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf 2 Homolog (DKK2) (AA 124-173) antibodyDKK2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf 2 Homolog (DKK2) (AA 159-258) antibodyDKK2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf 2 Homolog (DKK2) (AA 38-258) antibodyDKK2 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Dickkopf 2 Homolog (DKK2) (C-Term) antibodyDKK2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf 2 Homolog (DKK2) (N-Term) antibodyDKK2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf 2 Homolog (DKK2) (AA 31-62), (N-Term) antibodyDKK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf 2 Homolog (DKK2) antibodyDKK2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf 2 Homolog (DKK2) antibodyDKK2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf 2 Homolog (DKK2) antibodyDKK2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1833CT856-7-20 unconjugated
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应用备注
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Peptide ELISA: 1/8000. Western blot: 1 - 3 μg/mL. Approx 28 kDa band observed in Human Heart lysate (calculatedMW of 28.8 kDa according to NP_055236).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DKK2 (Dickkopf 2 Homolog (DKK2))
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别名
- Dickkopf-2 (DKK2)
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背景
- Analysis of individual DKK domains and chimeric DKKs shows that the carboxy-terminal domains of both DKK1 and DKK2 associate with LRP6 and are necessary and sufficient for Wnt8 inhibition. Xenopus Dickkopf 1 (DKK1) was initially discovered as a Wnt antagonist that plays an important role in head formation. By far, four members of DKK have been identified in mammals. Each DKK molecule contains two conserved cysteine-rich domains. Recent studies showed that the second Cys-rich domains of DKK1 and DKK2 inhibited Wnt3a-activated signaling, whereas the first Cys-rich domains had no effects. In addition, the second Cys-rich domain of DKK2, but not that of DKK1, was able to activate the canonical pathway in the presence of LRP6, and this LRP-dependent signaling does not require Dvl.Synonyms: Dickkopf-related protein 2, Dkk-2
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基因ID
- 27123
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NCBI登录号
- NP_055236
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UniProt
- Q9UBU2
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途径
- WNT signaling
抗原
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