电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

RACGAP1 抗体 (C-Term)

This 山羊 多克隆 antibody specifically detects RACGAP1 in WB, IHC (p) 和 EIA. It exhibits reactivity toward 人, Cow 和 犬.
产品编号 ABIN374167
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RACGAP1 抗体 (C-Term) (ABIN374167)

抗原

See all RACGAP1 抗体
RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

适用

  • 87
  • 39
  • 33
  • 8
  • 6
  • 5
  • 5
  • 5
  • 5
  • 2
  • 2
人, Cow, 犬

宿主

  • 96
  • 4
  • 1
  • 1
山羊

克隆类型

  • 86
  • 16
多克隆

标记

  • 50
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This RACGAP1 antibody is un-conjugated

应用范围

  • 89
  • 42
  • 40
  • 35
  • 27
  • 26
  • 22
  • 14
  • 13
  • 7
  • 6
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 19
    • 15
    • 9
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    C-GRQGNFFASP MLK

    特异性

    This antibody detects RACGAP1 at C-term.

    交叉反应 (详细)

    Species reactivity (expected):Canine (Dog) and Bovine.
    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide from the C Terminus of the protein sequence according to NP_037409.2, NP_001119576.1, NP_001119575.1. Genename: RACGAP1
  • 应用备注

    Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.1-0.3 μg/mL. Approx 60 kDa band observed in Human Testis lysates(calculated MW of 71.0 kDa according to NP_037409.2). The observed molecular weightcorresponds to earlier findings in literature with different antibodies (Toure et al. , J BiolChem 1998 Mar 13,273(11): 6019-23, PMID: 9497316). Immunohistochemistry: 1 μg/mL. In paraffin embedded Human Testis, shows nuclearstaining of many cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

    别名

    RACGAP1

    背景

    Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.Synonyms: KIAA1478, MGCRACGAP, Male germ cell RacGap, Rac GTPase-activating protein 1

    分子量

    71kDa (NP_037409).

    基因ID

    29127

    NCBI登录号

    NP_037409

    UniProt

    Q9H0H5

    途径

    Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
You are here: