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FOXP3 抗体 (C-Term)

This anti-FOXP3 antibody is a 山羊 多克隆 antibody detecting FOXP3 in WB 和 EIA. Suitable for 人, Pig 和 犬.
产品编号 ABIN374156
发货至: 中国

Quick Overview for FOXP3 抗体 (C-Term) (ABIN374156)

抗原

See all FOXP3 抗体
FOXP3 (Forkhead Box P3 (FOXP3))

适用

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人, Pig, 犬

宿主

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山羊

克隆类型

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多克隆

标记

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This FOXP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    序列

    SQRPSRCSNP TPGP

    特异性

    This antibody is expected to recognize both reported isoforms (NP_054728.2 and NP_001107849.1).

    交叉反应 (详细)

    Species reactivity (expected):Canine (Dog) and Pig.
    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide from C-Terminus of the protein sequence according to NP_054728.2, NP_001107849.1. Genename: FOXP3
  • 应用备注

    Peptide ELISA: Limit Dilution: 1/16000. Immunohistochemistry: 0.3-1 μg/mL. In paraffin embedded Human Tonsil, stains nuclei ofsome cells in the interfollicular area.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FOXP3 (Forkhead Box P3 (FOXP3))

    别名

    FOXP3

    背景

    FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.Synonyms: Forkhead box protein P3, IPEX, JM2, Scurfin

    基因ID

    50943

    NCBI登录号

    NP_054728

    UniProt

    Q9BZS1

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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