BAG2 抗体 (C-Term)
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Quick Overview for BAG2 抗体 (C-Term) (ABIN374110)
抗原
See all BAG2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- CSKTLQQNAE SRFN
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特异性
- This antibody detects BAG2 at C-term.
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from C Terminus of the protein sequence according to NP_004273.1. Genename: BAG2
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应用备注
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Peptide ELISA: Limit dilution 1: 8000. Western blot: 0.1-0.3 μg/mL. Approx 25 kDa band observed in Human HeLa lysates(calculated MW of 23.5 kDa according to NP_004273.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- BAG2 (BCL2-Associated Athanogene 2 (BAG2))
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别名
- BAG2
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背景
- BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.Synonyms: BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2
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基因ID
- 9532
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NCBI登录号
- NP_004273
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UniProt
- O95816
抗原
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