SH3GLB1 抗体 (C-Term)
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北京 101111
Quick Overview for SH3GLB1 抗体 (C-Term) (ABIN374106)
抗原
See all SH3GLB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-QKGKVPITYL ELLN
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特异性
- This antibody detects BIF1 / Endophilin-B1 at C-term.
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from the C Terminus of the protein sequence according to NP_057093.1 Genename: SH3GLB1
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应用备注
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Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.3-1.0 μg/mL. Approx 38 kDa band observed in lysates of Human T cell lineJurkat and in Human Lung and Placenta (calculated MW of 40.8 kDa according toNP_057093.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
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别名
- Endophilin-B1
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背景
- Bif is a member of the endophilin B protein family and may be an important component of the mitochondrial pathway for apoptosis, as a novel Bax/Bak activator. The loss of this proapoptotic molecule may contribute to tumorigenesis. Endophilins have been proposed to play roles in membrane trafficking reactions through interactions with endocytic protein via physical or chemical modifications of the membrane bilayer, particularly in presynaptic vesicle trafficking at nerve terminals. Bif (Endophilin B1), like endophilins A, binds to palmitoyl CoA and exhibits lysophosphatidic acid acyl transferase activity.Synonyms: BIF1, Bax-interacting factor 1, Bif-1, KIAA0491, SH3 domain-containing GRB2-like protein B1, SH3GLB1
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基因ID
- 51100
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NCBI登录号
- NP_057093
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UniProt
- Q9Y371
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途径
- Autophagy
抗原
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