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SH3GLB1 抗体 (C-Term)

This anti-SH3GLB1 antibody is a 山羊 多克隆 antibody detecting SH3GLB1 in WB. Suitable for 人, 小鼠, 大鼠, Cow 和 犬.
产品编号 ABIN374106
发货至: 中国

Quick Overview for SH3GLB1 抗体 (C-Term) (ABIN374106)

抗原

See all SH3GLB1 抗体
SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

适用

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人, 小鼠, 大鼠, Cow, 犬

宿主

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山羊

克隆类型

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多克隆

标记

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This SH3GLB1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    C-QKGKVPITYL ELLN

    特异性

    This antibody detects BIF1 / Endophilin-B1 at C-term.

    纯化方法

    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

    免疫原

    Peptide from the C Terminus of the protein sequence according to NP_057093.1 Genename: SH3GLB1
  • 应用备注

    Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.3-1.0 μg/mL. Approx 38 kDa band observed in lysates of Human T cell lineJurkat and in Human Lung and Placenta (calculated MW of 40.8 kDa according toNP_057093.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • 抗原

    SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

    别名

    Endophilin-B1

    背景

    Bif is a member of the endophilin B protein family and may be an important component of the mitochondrial pathway for apoptosis, as a novel Bax/Bak activator. The loss of this proapoptotic molecule may contribute to tumorigenesis. Endophilins have been proposed to play roles in membrane trafficking reactions through interactions with endocytic protein via physical or chemical modifications of the membrane bilayer, particularly in presynaptic vesicle trafficking at nerve terminals. Bif (Endophilin B1), like endophilins A, binds to palmitoyl CoA and exhibits lysophosphatidic acid acyl transferase activity.Synonyms: BIF1, Bax-interacting factor 1, Bif-1, KIAA0491, SH3 domain-containing GRB2-like protein B1, SH3GLB1

    基因ID

    51100

    NCBI登录号

    NP_057093

    UniProt

    Q9Y371

    途径

    Autophagy
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