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GZMB 抗体 (N-Term)

The 兔 多克隆 anti-GZMB antibody is suitable to detect GZMB in samples from 人, 小鼠 和 大鼠. It has been validated for IHC (p).
产品编号 ABIN372968
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GZMB 抗体 (N-Term) (ABIN372968)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

适用

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人, 小鼠, 大鼠

宿主

  • 107
  • 96
  • 4

克隆类型

  • 123
  • 84
多克隆

标记

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This GZMB antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 50
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    N-Term

    特异性

    This antibody reacts to Granzyme B.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    A synthetic peptide from N-terminus of human Granzyme B
  • 应用备注

    Immunohistochemistry on paraffin sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM PBS, pH 7.4, BSA, sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    GZMB (Granzyme B (GZMB))

    背景

    Granzyme B is a cysteine protease found in the cytoplasmic lysosome-like granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells and is is required for the induction of target cell lysis. This occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E

    基因ID

    3002

    NCBI登录号

    NP_004122

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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