PDGFRA 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for PDGFRA 抗体 (C-Term) (ABIN372897)
抗原
See all PDGFRA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
-
This antibody is specific for PDGFR alpha and does not react with PDGFR beta.
Cellular Localization: Cytoplasmic and cell membrane. -
交叉反应 （详细）
-
Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography
-
免疫原
- A synthetic peptide derived from C-terminal of Human PDGFR alpha.
-
亚型
- IgG
-
-
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 179-361) antibody
PDGFRA 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5B11G5 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 361-528) antibodyPDGFRA 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8E12F2 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 698-727) antibodyPDGFRA 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB11101 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 331-719) antibodyPDGFRA 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 179-361) antibodyPDGFRA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A10A8 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1048-1077), (C-Term) antibodyPDGFRA 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB2005-2006 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1048-1077) antibodyPDGFRA 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1021-1089) antibodyPDGFRA 适用: 人, 小鼠, 大鼠, 犬 ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 25-218) antibodyPDGFRA 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4H1-1C9 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1-1089) antibodyPDGFRA 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western blot: 1 μg/mL for 2 hrs at RT. Immunohistochemistry on Paraffin Sections: 5 μg/mL for 45 min at RT. Staining offormalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0 for10-20 min followed by cooling at RT for 20 min. Positive Control: Ovarian carcinoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, pH 7.6, 0.2 % BSA, 15 mM sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
-
别名
- CD140a / PDGFRA
-
背景
- Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation, and also lead to activation of the Ras, Raf and ERK 1 and 2 pathway.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha
-
基因ID
- 5156
-
NCBI登录号
- NP_006197
-
UniProt
- P16234
-
途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
抗原
-
