TFEC 抗体 (Internal Region)
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Quick Overview for TFEC 抗体 (Internal Region) (ABIN372800)
抗原
See all TFEC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- Recognizes Transcription Factor EC (TFEC).
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交叉反应 （详细）
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Species reactivity (expected):Rat.
Species reactivity (tested):Mouse. -
纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic peptide (C-HITKQQTHPERN) from an Internal region of Mouse TFEC.
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亚型
- IgG
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anti-Transcription Factor EC (TFEC) (AA 1-89) antibody
TFEC 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4F11 unconjugated
anti-Transcription Factor EC (TFEC) (Internal Region) antibodyVerified TFEC 适用: 人, 小鼠 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Transcription Factor EC (TFEC) (N-Term) antibodyTFEC 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EC (TFEC) (AA 179-205) antibodyTFEC 适用: 人 WB 宿主: 兔 Polyclonal RB40605 unconjugated
anti-Transcription Factor EC (TFEC) (N-Term) antibodyVerified TFEC 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Transcription Factor EC (TFEC) (AA 1-197) antibodyTFEC 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EC (TFEC) (AA 71-120) antibodyTFEC 适用: 人, 大鼠, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- TFEC (Transcription Factor EC (TFEC))
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别名
- TFEC
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背景
- The DNA-binding factor TFE3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. TFE3 is ubiquitously expressed and can directly associates with DNA as either homodimers or heterodimers formed with two related proteins, TFEB or TFEC. TFE3 binds to and activates the microE3 motif of the immunoglobulin heavy-chain enhancer to induce B-cell-specific gene transcription and DNA recombination. TFEB binds to the major late promoter of adenovirus and specifically associates with DNA as both a homodimer and a heterodimer with TFE3. TFEB is expressed at low levels in the embryo but at high levels in the trophoblast cells of the placenta, where it plays a critical role in regulating normal vascularization of the placenta. TFEC shares a bHLH/LZ structure with TFE3 and a closely related protein microphthalmia-associated transcription factor (MITF), which is critically involved in melanocyte differentiation. Unlike TFE3, the expression of TFEC is largely restricted to fibroblasts, myoblasts, chondrosarcoma cells, and myeloma cells.Synonyms: TCFEC, TFE-C, TFEC-L, TFECL, Transcription factor EC, Transcription factor EC-like
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基因ID
- 21426
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NCBI登录号
- NP_112475
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UniProt
- Q9WTW4
抗原
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