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TFEC 抗体 (Internal Region)

TFEC 适用: 小鼠, 大鼠 IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN372800
发货至: 中国
  • 抗原 See all TFEC 抗体
    TFEC (Transcription Factor EC (TFEC))
    抗原表位
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 23
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 20
    • 2
    • 1
    山羊
    克隆类型
    • 22
    • 1
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    This TFEC antibody is un-conjugated
    应用范围
    • 18
    • 16
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Recognizes Transcription Factor EC (TFEC).
    交叉反应 (详细)
    Species reactivity (expected):Rat.
    Species reactivity (tested):Mouse.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide (C-HITKQQTHPERN) from an Internal region of Mouse TFEC.
    亚型
    IgG
    Top Product
    Discover our top product TFEC Primary Antibody
  • 应用备注
    ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    TFEC (Transcription Factor EC (TFEC))
    别名
    TFEC (TFEC 产品)
    别名
    si:ch211-238e6.5 antibody, TFEC antibody, TCFEC antibody, TFE-C antibody, TFEC-L antibody, TFECL antibody, bHLHe34 antibody, hTFEC-L antibody, BB107417 antibody, Tcfec antibody, transcription factor EC antibody, tfec antibody, TFEC antibody, Tfec antibody
    背景
    The DNA-binding factor TFE3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. TFE3 is ubiquitously expressed and can directly associates with DNA as either homodimers or heterodimers formed with two related proteins, TFEB or TFEC. TFE3 binds to and activates the microE3 motif of the immunoglobulin heavy-chain enhancer to induce B-cell-specific gene transcription and DNA recombination. TFEB binds to the major late promoter of adenovirus and specifically associates with DNA as both a homodimer and a heterodimer with TFE3. TFEB is expressed at low levels in the embryo but at high levels in the trophoblast cells of the placenta, where it plays a critical role in regulating normal vascularization of the placenta. TFEC shares a bHLH/LZ structure with TFE3 and a closely related protein microphthalmia-associated transcription factor (MITF), which is critically involved in melanocyte differentiation. Unlike TFE3, the expression of TFEC is largely restricted to fibroblasts, myoblasts, chondrosarcoma cells, and myeloma cells.Synonyms: TCFEC, TFE-C, TFEC-L, TFECL, Transcription factor EC, Transcription factor EC-like
    基因ID
    21426
    NCBI登录号
    NP_112475
    UniProt
    Q9WTW4
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