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TFEC 抗体 (AA 179-205)

TFEC 适用: 人 WB 宿主: 兔 Polyclonal RB40605 unconjugated
产品编号 ABIN1881878
发货至: 中国
  • 抗原 See all TFEC 抗体
    TFEC (Transcription Factor EC (TFEC))
    抗原表位
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 179-205
    适用
    • 22
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 19
    • 2
    • 1
    克隆类型
    • 21
    • 1
    多克隆
    标记
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    This TFEC antibody is un-conjugated
    应用范围
    • 17
    • 16
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    C, M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This TFEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-205 amino acids from the Central region of human TFEC.
    克隆位点
    RB40605
    亚型
    Ig Fraction
    Top Product
    Discover our top product TFEC Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Mansky, Sulzbacher, Purdom, Nelsen, Hume, Rehli, Ostrowski: "The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter." in: Journal of leukocyte biology, Vol. 71, Issue 2, pp. 304-10, (2002) (PubMed).

    Chung, Kim, Kawamoto: "TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells." in: Biochemistry, Vol. 40, Issue 30, pp. 8887-97, (2001) (PubMed).

    Steingrímsson, Tessarollo, Reid, Jenkins, Copeland: "The bHLH-Zip transcription factor Tfeb is essential for placental vascularization." in: Development (Cambridge, England), Vol. 125, Issue 23, pp. 4607-16, (1999) (PubMed).

  • 抗原
    TFEC (Transcription Factor EC (TFEC))
    别名
    TFEC (TFEC 产品)
    别名
    si:ch211-238e6.5 antibody, TFEC antibody, TCFEC antibody, TFE-C antibody, TFEC-L antibody, TFECL antibody, bHLHe34 antibody, hTFEC-L antibody, BB107417 antibody, Tcfec antibody, transcription factor EC antibody, tfec antibody, TFEC antibody, Tfec antibody
    背景
    Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo-or heterodimeric form.
    分子量
    38788
    NCBI登录号
    NP_001018068, NP_001231512, NP_036384
    UniProt
    O14948
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