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OGG1 抗体 (Internal Region)

OGG1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN372767
发货至: 中国
  • 抗原 See all OGG1 抗体
    OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
    抗原表位
    • 16
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 51
    • 25
    • 24
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 48
    • 5
    • 1
    山羊
    克隆类型
    • 44
    • 10
    多克隆
    标记
    • 26
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OGG1 antibody is un-conjugated
    应用范围
    • 38
    • 14
    • 14
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Recognizes 8-oxoguanine DNA Glycosylase Homolog 1 (OGG1).
    交叉反应 (详细)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human, Rat.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide (C-HPKTSQAKGPSPLANK) from an Internal region of Mouse OGG1.
    亚型
    IgG
    Top Product
    Discover our top product OGG1 Primary Antibody
  • 应用备注
    ELISA: 1/28000. Western Blot: 0.1-0.3 μg/mL. Immunohistochemistry on Paraffin Sections: 2.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris Saline Buffer, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
    别名
    OGG1 (OGG1 产品)
    别名
    OGG1 antibody, zgc:158858 antibody, 8-oxoguanine-DNA glycosylase 1 antibody, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 antibody, ATOGG1 antibody, F8K7.14 antibody, F8K7_14 antibody, 19.m02329 antibody, DDBDRAFT_0184479 antibody, DDBDRAFT_0233024 antibody, DDB_0184479 antibody, DDB_0233024 antibody, ogg1 antibody, Tb04.1H19.930 antibody, HMMH antibody, HOGG1 antibody, MUTM antibody, OGH1 antibody, Mmh antibody, 8-oxoguanine DNA glycosylase antibody, 8-oxoguanine DNA glycosylase L homeolog antibody, 8-oxoguanine-DNA glycosylase 1 antibody, 8-OXOGUANINE DNA GLYCOSYLASE antibody, putative 8-oxoguanine DNA glycosylase antibody, 8-oxoguanine DNA-glycosylase antibody, N-glycosylase/DNA lyase OGG1 antibody, 8-oxoguanine DNA-glycosylase 1 antibody, OGG1 antibody, ogg1.L antibody, ogg1 antibody, ECU08_0770 antibody, CA_C2707 antibody, BBOV_I004290 antibody, Smp_074010.1 antibody, LOC9329243 antibody, Tb927.4.2480 antibody, Ogg1 antibody
    背景
    The Ogg1 gene encodes a DNA repair enzyme (N glycosylase/DNA lyase) that incises DNA at 8 oxoG residues. N glycosylase/DNA lyase excises 7,8 dihydro 8 oxoguanine and 2,6 diamino 4 hydroxy 5 N methylformamidopyrimidine (FAPY) from damaged DNA. N glycosylase/DNA lyase has a beta lyase activity that nicks DNA 3' to the lesion. Alternative splicing of the C terminal region of the Ogg1 gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N terminal region in common. Many alternative splice variants for this gene have been described, but the full length nature for every variant has not been determined. The N terminus of this gene contains a mitochondrial targetting signal, essential for mitochondrial localization.Synonyms: MMH, MUTM, N-glycosylase/DNA lyase, OGH1
    基因ID
    81528
    NCBI登录号
    NP_110497
    UniProt
    O70249
    途径
    DNA Damage Repair
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