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Vimentin 抗体

This anti-Vimentin antibody is a 小鸡 多克隆 antibody detecting Vimentin in WB, IF 和 IHC (fro). Suitable for 人, 小鼠, 大鼠 和 哺乳动物. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN372741
发货至: 中国

Quick Overview for Vimentin 抗体 (ABIN372741)

抗原

See all Vimentin (VIM) 抗体
Vimentin (VIM)

适用

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人, 小鼠, 大鼠, 哺乳动物

宿主

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小鸡

克隆类型

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多克隆

标记

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This Vimentin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    Specific for the ~50 kDa Vimentin protein.

    交叉反应 (详细)

    Species reactivity (expected):other Mammalian.
    Species reactivity (tested):Human, Mouse and Rat.

    纯化方法

    Ig Fraction

    免疫原

    Recombinant human Vimentin purified from E. coli.

    亚型

    Ig Fraction
  • 应用备注

    Western blotting: 1/1,000. Immunofluorescence: 1/500. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at-20 °C.
  • Plitzko, Havemeyer, Kunze, Clement: "The pivotal role of the mitochondrial amidoxime reducing component 2 in protecting human cells against apoptotic effects of the base analog N6-hydroxylaminopurine." in: The Journal of biological chemistry, Vol. 290, Issue 16, pp. 10126-35, (2015) (PubMed).

    Kang, Taldone, Patel, Patel, Rodina, Gozman, Maharaj, Clement, Patel, Brodsky, Young, Chiosis: "Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70." in: Journal of medicinal chemistry, Vol. 57, Issue 4, pp. 1188-207, (2014) (PubMed).

    Kirane, Toombs, Ostapoff, Carbon, Zaknoen, Braunfeld, Schwarz, Burrows, Brekken: "Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 18, pp. 5031-42, (2012) (PubMed).

  • 抗原

    Vimentin (VIM)

    别名

    Vimentin

    背景

    Vimentin is the major protein subunit of the 10nm or intermediate filaments (IFs) found in many kinds of mesenchymal and epithelial cells as well as developing neuronal and astrocytic precursor cells in the CNS. Vimentin is thought to be critically involved in lymphocyte adhesion and transmigration (Nieminen M et al. 2006). Copolymers are frequently formed between vimentin and other IFs, such as GFAP (in many kinds of astrocytes), desmin (in muscle cells) and neurofilament proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and generally to reveal the filamentous cytoskeleton. Recent studies suggest that vimentin affects prostate cancer cells motility and invasiveness (Zhao et al. 2008).Synonyms: VIM

    基因ID

    81818

    NCBI登录号

    NP_112402

    UniProt

    P31000

    途径

    Caspase Cascade in Apoptosis
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