PLK1 抗体 (pThr210)
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- 抗原 See all PLK1 抗体
- PLK1 (Polo-Like Kinase 1 (PLK1))
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抗原表位
- pThr210
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 非洲爪蟾, Non-Human Primate
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody recognizes the ~66k PLK protein phosphorylated at Thr210. Immunolabeling of the PLK band is completely blocked by lambda-phosphatase treatment.
- 交叉反应 （详细）
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Species reactivity (expected):Bovine, Canine, Mouse, Xenopus, Zebrafish and non-Human Primates.
Species reactivity (tested):Rat and Human. - 纯化方法
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
- 免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr210 of PLK1.
- 亚型
- IgG
- Top Product
- Discover our top product PLK1 Primary Antibody
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anti-Polo-Like Kinase 1 (PLK1) (AA 331-508) antibody
PLK1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Polo-Like Kinase 1 (PLK1) (AA 1-603) antibodyPLK1 适用: 人 WB, ELISA, IF, IP, PLA 宿主: 小鼠 Monoclonal 2G12 unconjugated
anti-Polo-Like Kinase 1 (PLK1) (AA 1-603) antibodyPLK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Polo-Like Kinase 1 (PLK1) antibodyPLK1 适用: 人 WB, IHC, IHC (p), IP, FACS 宿主: 小鼠 Monoclonal 5C1 unconjugated
anti-Polo-Like Kinase 1 (PLK1) antibodyPLK1 适用: 人 WB, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 1D4 unconjugated
anti-Polo-Like Kinase 1 (PLK1) antibodyPLK1 适用: 人, 犬 WB, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 6C6 unconjugated
anti-Polo-Like Kinase 1 (PLK1) (AA 304-603) antibodyPLK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Polo-Like Kinase 1 (PLK1) antibodyPLK1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Polo-Like Kinase 1 (PLK1) antibodyPLK1 适用: 人, 犬, 猴 WB, IF, IP, FACS 宿主: 小鼠 Monoclonal 8C12 unconjugated
anti-Polo-Like Kinase 1 (PLK1) (AA 205-214), (pThr210) antibodyPLK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- 抗原
- PLK1 (Polo-Like Kinase 1 (PLK1))
- 别名
- PLK1 (PLK1 产品)
- 别名
- PLK antibody, STPK13 antibody, plk antibody, PLK-1 antibody, Plx1 antibody, stpk13 antibody, Plk antibody, cb525 antibody, cb636 antibody, ik:tdsubc_2d1 antibody, wu:fb37g11 antibody, wu:fb76g03 antibody, xx:tdsubc_2d1 antibody, polo like kinase 1 antibody, polo like kinase 1 S homeolog antibody, polo-like kinase 1 antibody, polo-like kinase 1 (Drosophila) antibody, Serine/threonine-protein kinase plk-1 antibody, PLK1 antibody, plk1.S antibody, plk1 antibody, Plk1 antibody, plk-1 antibody
- 背景
- Polo-like kinases are important regulators of cell cycle progression. PLK1 is a highly conserved Ser/Thr kinase that has essential roles in the formation of mitotic bipolar spindles (van Vugt et al., 2004). Deregulated expression of PLK's is detected in many types of cancer and associated with oncogenesis (Takei et al., 2005). It has been proposed that PLK1 function is altered at different stages of mitosis through consecutive phosphorylation events at Ser137 and Thr210 (van de Weerdt et al., 2005).Synonyms: PLK-1, Polo-like kinase 1, STPK13, Serine/threonine-protein kinase PLK1
- 基因ID
- 5347
- NCBI登录号
- NP_005021
- UniProt
- P53350
- 途径
- Cell Division Cycle, M Phase
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