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Peripherin 抗体

This anti-Peripherin antibody is a 小鸡 多克隆 antibody detecting Peripherin in WB, IF 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN372702
发货至: 中国

Quick Overview for Peripherin 抗体 (ABIN372702)

抗原

See all Peripherin (PRPH) 抗体
Peripherin (PRPH)

适用

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大鼠

宿主

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小鸡

克隆类型

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多克隆

标记

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This Peripherin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 交叉反应 (详细)

    Species reactivity (expected):many Mammalian.
    Species reactivity (tested):Rat.

    纯化方法

    Ig Fraction

    免疫原

    Recombinant rat peripherin expressed in and purified from E. coli.

    亚型

    Ig Fraction
  • 应用备注

    Western blot: 1/1000. Immunofluorescence: 1/500. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原

    Peripherin (PRPH)

    别名

    Peripherin

    背景

    Peripherin is a ~57 kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems, which gives the protein its name. Subsequently, peripherin was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. In contrast to the neurofilaments, peripherin is strongly up-regulated after nerve injury (1). Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors (2). Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes (3). Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration.Synonyms: NEF4, PRPH, PRPH1

    基因ID

    10116

    UniProt

    P21807
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