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MAP2 抗体

This anti-MAP2 antibody is a 小鸡 多克隆 antibody detecting MAP2 in WB, IF 和 IHC (fro). Suitable for 人, 小鼠, 大鼠 和 Cow. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN372661
发货至: 中国

Quick Overview for MAP2 抗体 (ABIN372661)

抗原

See all MAP2 抗体
MAP2 (Microtubule-Associated Protein 2 (MAP2))

适用

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人, 小鼠, 大鼠, Cow

宿主

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小鸡

克隆类型

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多克隆

标记

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This MAP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    This antibody is specific for the ~280k MAP2 protein.

    交叉反应 (详细)

    Species reactivity (tested):Bovine, Human, Mouse and Rat.

    纯化方法

    Ig Fraction

    免疫原

    Bovine MAP2 isolated from brain by the GTP microtubule cycling method.

    亚型

    Ig Fraction
  • 应用备注

    Western blot: 1/20,000. Immunohistochemistry. Immunofluorescence: 1/2,500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at-20 °C.
  • Klüssendorf, Song, Schau, Morellini, Dityatev, Koliwer, Kreienkamp: "The Golgi-Associated PDZ Domain Protein Gopc/PIST Is Required for Synaptic Targeting of mGluR5." in: Molecular neurobiology, Vol. 58, Issue 11, pp. 5618-5634, (2022) (PubMed).

    Jacquemet, Paatero, Carisey, Padzik, Orange, Hamidi, Ivaska: "FiloQuant reveals increased filopodia density during breast cancer progression." in: The Journal of cell biology, Vol. 216, Issue 10, pp. 3387-3403, (2017) (PubMed).

  • 抗原

    MAP2 (Microtubule-Associated Protein 2 (MAP2))

    别名

    MAP-2

    背景

    Microtubules are 25nm diameter protein rods found in most kinds of eukaryotic cells. They are polymerized from a dimeric subunit made of one a subunit and one b tubulin subunit. Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein tau and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5 (Kindler & Gardner 1994). MAP2 is made up of two ~280 kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70 kDa on SDS-PAGE gels. All these MAP2 forms are derived from a single gene by alternate transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein tau. MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. MAP2 has been recently shown to be the specific receptor for the neurosteroid pregnenolone (Fontaine-Lenore V. et al., 2006).Synonyms: MAP2, Microtubule-associated protein 2, Neuronal Marker

    基因ID

    4133

    NCBI登录号

    NP_002365

    UniProt

    P11137
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