SLC6A1 抗体 (C-Term)
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Quick Overview for SLC6A1 抗体 (C-Term) (ABIN372646)
抗原
See all SLC6A1 (GAT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Specific for the ~67k GAT-1 protein. Immunolabeling is blocked by the peptide used as antigen.
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交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Rat. -
纯化方法
- Affinity Chromatography.
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免疫原
- Peptide corresponding to amino acid residues from the C-terminal region of rat GAT-1.
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亚型
- IgG
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anti-GABA Transporter 1 (GAT1) (N-Term) antibody
GAT1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) (AA 585-599) antibodyKO Validated GAT1 适用: 大鼠, 小鼠 WB, IHC, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) antibodyGAT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) antibodyGAT1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) (2nd Extracellular Loop), (AA 194-206) antibodyGAT1 适用: 大鼠 WB, IHC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) (2nd Extracellular Loop), (AA 194-206) antibodyGAT1 适用: 大鼠 WB, IHC 宿主: 豚鼠 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) (AA 585-599) antibodyGAT1 适用: 大鼠, 小鼠 WB, IHC (p), IP, ICC 宿主: 豚鼠 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) antibodyGAT1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2390 unconjugated Recombinant Antibody
anti-GABA Transporter 1 (GAT1) (Middle Region) antibodyGAT1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) (AA 251-300) antibodyGAT1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 猴, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/1000. Immunohistochemitsry: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))
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别名
- GAT1 / SLC6A1
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背景
- Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia (Minelli et al., 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003).Synonyms: GABA transporter 1, GABATR, GABT1, GAT-1, Sodium- and chloride-dependent GABA transporter 1, Solute carrier family 6 member 1
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基因ID
- 79212
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NCBI登录号
- NP_077347
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UniProt
- P23978
抗原
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