GABBR2 抗体 (pSer783)
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Quick Overview for GABBR2 抗体 (pSer783) (ABIN372643)
抗原
See all GABBR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer783
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特异性
- Specific for ~102k GABAB R2 phosphorylated at Ser783. Immunolabeling of the GABAB R2 band is completely blocked by lambda-phosphatase treatment.
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交叉反应 （详细）
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Species reactivity (expected):Human, Bovine, Chicken, Mouse, Xenopus and non-Human Primates.
Species reactivity (tested):Rat. -
纯化方法
- Sequential Chromatography on phospho- and dephospho-peptide affinity columns.
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免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser783 of GABAB R2.
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亚型
- IgG
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anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody
GABBR2 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 5G7F7 unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 501-650) antibodyGABBR2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (pSer783) antibodyGABBR2 适用: 大鼠 WB, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibodyGABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (HRP)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 HRP
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (FITC)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 FITC
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (Biotin)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 Biotin
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (PE)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 PE
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (PerCP)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 PerCP
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (APC)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 APC
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应用备注
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Western Blot: 1/1000. Immunofluorescence: 1/500 (See Ref.1)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
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别名
- GABBR2
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背景
- Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. It has recently been demonstrated that AMPK binds directly to GABAB receptors and phosphorylates S783 in the cytoplasmic tail of the R2 subunit and that S783 plays a critical role in enhancing neuronal survival after ischemia as phosphorylation of S783 is evident in many brain regions and is increased dramatically after ischemic injury to the brain (Kuramoto et al., 2007).Synonyms: G-protein coupled receptor 51, GABA-B receptor 2, GABA-B-R2, GABBR-2, GPR51, GPRC3B, Gamma-aminobutyric acid type B receptor subunit 2, Gb2, HG20
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基因ID
- 83633
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NCBI登录号
- NP_113990
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UniProt
- O88871
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途径
- cAMP Metabolic Process
抗原
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