Ephrin B1 抗体 (pTyr317)
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Quick Overview for Ephrin B1 抗体 (pTyr317) (ABIN372620)
抗原
See all Ephrin B1 (EFNB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr317
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特异性
- Specific for the ~46k Ephrin-B protein phosphorylated at Tyr317. Immunolabeling of the Ephrin-B band is blocked by lambda-phosphatase treatment
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交叉反应 （详细）
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Species reactivity (expected):Human, Bovine, Chicken, Mouse, Xenopus and Zebrafish.
Species reactivity (tested):Rat. -
纯化方法
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
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免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho Tyr317 of Chicken Ephrin-B.
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亚型
- IgG
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anti-Ephrin B1 (EFNB1) (AA 28-237) antibody
EFNB1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr324) antibodyEFNB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr324), (pTyr329) antibodyEFNB1 适用: 人 WB, ELISA, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr317) antibodyEFNB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr330) antibodyEFNB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (AA 259-346) antibodyEFNB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) antibodyEFNB1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr317) antibodyEFNB1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (Ser312) antibodyEFNB1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (AA 179-228) antibodyEFNB1 适用: 人, 小鼠, 犬, 猴, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- Ephrin B1 (EFNB1)
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别名
- Ephrin-B1
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背景
- Ephrin-B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development (Flanagan and Vancerhaeghen, 1998, Dufour et al., 2003, Oike et al., 2002). Ephrin-B molecules expressed at the membrane surface bind to the EphB family receptors on target cells during cell-to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin-B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin-B is thought to be a critical component of this reverse signaling event (Palmer et al., 2002). Recent work suggests that phosphorylation of a specific Ephrin-B residue (Tyr298) plays a key role in Ephrin-B signaling (Kalo, et al., 2001).Synonyms: CEK5 LIgand, CEK5-L, EFL-3, EFL3, EFNB1, ELK-L, EPH-related receptor tyrosine kinase ligand 2, EPLG2, LERK-2, LERK2
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基因ID
- 395896
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NCBI登录号
- NP_990366
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UniProt
- O73612
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途径
- RTK signaling
抗原
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