Ephrin B1 抗体 (pTyr298)
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- 抗原 See all Ephrin B1 (EFNB1) 抗体
- Ephrin B1 (EFNB1)
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抗原表位
- pTyr298
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适用
- 人, 小鼠, 大鼠, 小鸡, 斑马鱼, Cow, 犬, 非洲爪蟾, Non-Human Primate
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Ephrin B1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Specific for the ~46k Ephrin-B protein phosphorylated at Tyr298. Immunolabeling of the Ephrin-B band is blocked by lambda-phosphatase treatment.
- 交叉反应 （详细）
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Species reactivity (expected):Human, Bovine, Canine, Chicken, Mouse, Xenopus, Zebrafish and non-Human Primates.
Species reactivity (tested):Rat. - 纯化方法
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
- 免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho Tyr298 of Xenopus Ephrin-B.
- 亚型
- IgG
- Top Product
- Discover our top product EFNB1 Primary Antibody
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anti-Ephrin B1 (EFNB1) (AA 28-237) antibody
EFNB1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr324) antibodyEFNB1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr317) antibodyEFNB1 适用: 人, 小鼠, 大鼠, 小鸡, 斑马鱼, Cow, Frog WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr331) antibodyEFNB1 适用: 人, 小鼠, 大鼠, 小鸡, 斑马鱼, Cow, Frog WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr298) antibodyEFNB1 适用: 人, 小鼠, 大鼠, 小鸡, 斑马鱼, Cow, 犬, Frog, 灵长类 WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr317) antibodyEFNB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr330) antibodyEFNB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) antibodyEFNB1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (AA 28-237) antibodyEFNB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) antibodyEFNB1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- 抗原
- Ephrin B1 (EFNB1)
- 别名
- Ephrin-B1 (EFNB1 产品)
- 别名
- EFNB1 antibody, LERK2 antibody, Cek5-L antibody, EFL-3 antibody, Elk-L antibody, Epl2 antibody, Eplg2 antibody, LERK-2 antibody, Lerk2 antibody, Stra1 antibody, CFND antibody, CFNS antibody, EFL3 antibody, EPLG2 antibody, cfnd antibody, cfns antibody, efl3 antibody, efnb1-A antibody, ephrinB1 antibody, eplg2 antibody, lerk2 antibody, ephrin B1 antibody, ephrin-B1 antibody, ephrin-B1 L homeolog antibody, EFNB1 antibody, Efnb1 antibody, efnb1 antibody, efnb1.L antibody
- 背景
- Ephrin-B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development (Flanagan and Vancerhaeghen, 1998, Dufour et al., 2003, Oike et al., 2002). Ephrin-B molecules expressed at the membrane surface bind to the EphB family receptors on target cells during cell-to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin-B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin-B is thought to be a critical component of this reverse signaling event (Palmer et al., 2002). Recent work suggests that phosphorylation of a specific Ephrin-B residue (Tyr298) plays a key role in Ephrin-B signaling (Kalo, et al., 2001).Synonyms: CEK5 LIgand, CEK5-L, EFL-3, EFL3, EFNB1, ELK-L, EPH-related receptor tyrosine kinase ligand 2, EPLG2, LERK-2, LERK2
- 基因ID
- 394292
- NCBI登录号
- NP_001080948
- UniProt
- O13097
- 途径
- RTK signaling
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