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ELK1 抗体 (pSer383)

ELK1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Non-Human Primate WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372618
发货至: 中国
  • 抗原 See all ELK1 抗体
    ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
    抗原表位
    • 37
    • 28
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    pSer383
    适用
    • 166
    • 102
    • 94
    • 11
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    • 6
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    • 3
    • 2
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    人, 小鼠, 大鼠, 犬, 斑马鱼, Non-Human Primate
    宿主
    • 154
    • 11
    克隆类型
    • 144
    • 22
    多克隆
    标记
    • 87
    • 9
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    This ELK1 antibody is un-conjugated
    应用范围
    • 110
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    Western Blotting (WB)
    特异性
    Specific for ~46k Elk-1 phosphorylated at Ser383. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.
    交叉反应 (详细)
    Species reactivity (expected):Human, Canine, Mouse, Zebrafish and non-Human Primates.
    Species reactivity (tested):Rat.
    纯化方法
    Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
    免疫原
    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser383 of human Elk-1.
    亚型
    IgG
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  • 应用备注
    Western Blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原
    ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
    别名
    ELK1 (ELK1 产品)
    背景
    Elk-1 is a transcription factor involved in mediating gene transcription in response to growth factors (Hill and Treisman, 1995). Elk-1 is thought to be phosphorylated by MAP kinase at Ser383 and phosphorylation at this site is essential for the transcriptional activity of Elk-1 (Li et al., 2003). Phosphorylation of Elk-1 has also been implicated in synaptic plasticity in the adult hippocampus (Thiels et al., 2002).Synonyms: ETS domain-containing protein Elk-1, Elk-1
    基因ID
    2002
    NCBI登录号
    NP_001107595
    UniProt
    P19419
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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