DDC 抗体 (N-Term)
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Quick Overview for DDC 抗体 (N-Term) (ABIN372610)
抗原
See all DDC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Specific for the ~55k DDC protein.
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交叉反应 （详细）
- Species reactivity (tested):Bovine, Canine, Guinea Pig, Human, Rabbit, Rat and Sheep.
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纯化方法
- Affinity Chromatography using an AminoLink® Plus column matrix to which purified recombinant Bovine DDC was coupled.
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免疫原
- Peptide from N-terminus region of human DOPA decarboxylase (DDC), conjugated to keyhole limpet hemocyanin (KLH).
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亚型
- IgG
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anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 1-100) antibody
DDC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 32-61), (N-Term) antibodyDDC 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21702 unconjugated
anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 201-300) antibodyDDC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 200-420) antibodyDDC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) antibodyMicroarray verified DDC 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB783620 unconjugated
anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 1-480) antibodyDDC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8E8 unconjugated
anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (N-Term) antibodyDDC 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 24-215) antibodyDDC 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) antibodyMicroarray verified DDC 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB798726 unconjugated
anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) antibodyMicroarray verified DDC 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB534180 unconjugated
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应用备注
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Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
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别名
- AADC / DDC
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背景
- DOPA decarboxylase is an enzyme implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson's disease. Following the hydroxylation of tyrosine to form L dihydroxyphenylalanine (LDOPA), catalyzed by tyrosine hydroxylase, DDC decarboxylates LDOPA to form dopamine. This neurotransmitter is found in different areas of the brain and is particularly abundant in basal ganglia. Dopamine is also produced by DDC in the sympathetic nervous system and is the precursor of the catecholaminergic hormones, noradrenaline and adrenaline in the adrenal medulla. In the nervous system, tryptophan hydroxylase produces 5 OH tryptophan, which is decarboxylated by DDC, giving rise to serotonin. DDC is a homodimeric, pyridoxal phosphate dependent enzyme.Synonyms: Aromatic-L-amino-acid decarboxylase, DOPA decarboxylase
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基因ID
- 1644
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NCBI登录号
- NP_000781
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UniProt
- P20711
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途径
- Dopaminergic Neurogenesis
抗原
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