APP 抗体 (C-Term)
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Quick Overview for APP 抗体 (C-Term) (ABIN372589)
抗原
See all APP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Specific for ~115k APP protein. Immunolabeling of the APP protein band is completely blocked by preadsorption of the antibody with the peptide used as antigen.
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交叉反应 （详细）
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Species reactivity (expected):Human, Canine, Chicken, Mouse and non-Human Primates.
Species reactivity (tested):Rat. -
纯化方法
- Affinity Chromatography.
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免疫原
- Peptide corresponding to amino acid residues from the C-terminal region of rat APP.
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亚型
- IgG
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anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibody
APP 适用: 人 WB, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) antibodyAPP 适用: 人, 小鼠 WB, IHC, ELISA, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (AA 666-670) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (AA 18-270) antibodyAPP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (AA 381-480) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (pThr668) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) antibodyKD Validated APP 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1535 unconjugated Recombinant Antibody
anti-Amyloid beta (A4) Precursor Protein (APP) antibodyAPP 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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别名
- Amyloid beta A4 Protein / APP
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背景
- A large body of evidence has implicated the amyloid precursor protein (APP) in the pathogenesis of Alzheimer's disease (AD) (Kamenetz et al., 2003). The phosphorylation of APP at Thr668 is thought to play a critical role in generation of the soluble APP (beta) and beta-amyloid peptide (abeta) which are the major components of senile plaques in patient brains inflicted with AD (Liu et al., 2003, Ando et al., 2001).Synonyms: ABPP, APPI, Alzheimer disease amyloid protein, Amyloid Precursor Protein, CVAP, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II
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基因ID
- 54226
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NCBI登录号
- NP_062161
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UniProt
- P08592
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途径
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
抗原
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