IRAK2 抗体
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北京 101111
Quick Overview for IRAK2 抗体 (ABIN372430)
抗原
See all IRAK2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody recognizes Interleukin 1 Receptor-Associated Kinase 2 (IRAK2).
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Protein G Chromatography.
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免疫原
- Synthetic peptide of Human IRAK-2 - KLH conjugated.
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亚型
- IgG
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anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) antibody
IRAK2 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 111-210) antibodyIRAK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6C7 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (C-Term) antibodyIRAK2 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 211-458) antibodyIRAK2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) antibodyIRAK2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6365 unconjugated Recombinant Antibody
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 1-270) antibodyIRAK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 1-270) antibodyIRAK2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) antibodyIRAK2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) antibodyKD Validated IRAK2 适用: 人 WB 宿主: 小鼠 Monoclonal 25GB3735 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) antibodyIRAK2 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
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别名
- IRAK2
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背景
- The binding of interleukin-1 (IL-1) to its receptor IL-1RI initiates a signaling cascade that results in the activation of NF-kB. Recently protein kinases designated IRAKs (IL-1 receptor-associated kinases) have been identified and designated as IRAK-1, IRAK-2 and IRAK-M. IRAK-2 is a serine/threonine protein kinase. The primary amino acid sequence of IRAK-2 shares similarity with that of Pelle, a protein kinase that is essential for the activation of a NF-kB homolog in Drosophila. IRAK (IL-1 receptor kinase) and mediates NF-kB activation by members of IL-1 family including IL-1 and a novel cytokine IL-18. Disruption of IRAK expression by anti-sense oligonucleotides inhibits IL-1 and IL-18-induced activation of NF-kB and activator protein, AP-1.Synonyms: IRAK-2, Interleukin-1 receptor-associated kinase-like 2
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基因ID
- 3656
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NCBI登录号
- NP_001561
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UniProt
- O43187
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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