FOXO3 抗体 (AA 600-673)
Our Local Distributor
北京 101111
Quick Overview for FOXO3 抗体 (AA 600-673) (ABIN372285)
抗原
See all FOXO3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 600-673
-
特异性
- This antibody recognizes Forkhead Box O3 (FOXO3)
-
交叉反应 （详细）
-
Species reactivity (expected):Bovine, Chicken, Dog (Canine), Xenopus, Monkey, Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography.
-
免疫原
- Synthetic peptide corresponding to a portion of the amino acids 600-673 of human FOXO3A.
-
亚型
- IgG
-
-
anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyVerified FOXO3 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibodyFOXO3 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyKO Validated FOXO3 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) antibodyFOXO3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 1E2 unconjugated Recombinant Antibody
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 224-253) antibodyFOXO3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 2-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.05 % Sodium Azide as preservative and 0.05 % BSA as stabilizer.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- FOXO3 (Forkhead Box O3 (FOXO3))
-
别名
- FOXO3 / FKHRL1
-
背景
- FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two-tiered mechanism of phosphorylation and acetylation. FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors. It recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. FOXO3a has been shown to induce cell growth arrest to effect tumor suppression and FOXO3A genotype is strongly associated with human longevity.Synonyms: AF6q21 protein, FOXO3A, Forkhead box protein O3, Forkhead in rhabdomyosarcoma-like 1
-
分子量
- 71 kDa.
-
基因ID
- 2309
-
NCBI登录号
- NP_001446
-
UniProt
- O43524
-
途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
抗原
-
