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PKM2 抗体

This 山羊 多克隆 antibody specifically detects PKM2 in WB, IP, IHC (p) 和 EIA. It exhibits reactivity toward 人 和 兔.
产品编号 ABIN372199
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PKM2 抗体 (ABIN372199)

抗原

See all PKM2 抗体
PKM2 (Pyruvate Kinase M2 (PKM2))

适用

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  • 1
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人, 兔

宿主

  • 95
  • 24
  • 3
山羊

克隆类型

  • 88
  • 34
多克隆

标记

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This PKM2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody recognizes M1 and M2 Isoforms of Pyruvate Kinase (Rabbit Muscle).

    纯化方法

    IgG Fractionation.

    免疫原

    Pyruvate kinase purified from Rabbit muscle.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western Blot: 1/500-1/2000. Immunoprecipitation. ELISA: 1/4000-1/20000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    10.0 mg/mL

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    PKM2 (Pyruvate Kinase M2 (PKM2))

    别名

    PKM2

    背景

    PKM2 (pyruvate kinase, muscle) catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. It has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.Synonyms: CTHBP, Cytosolic thyroid hormone-binding protein, M2-PK, OIP-3, OIP3, Opa-interacting protein 3, PK2, PK3, PKM, Pyruvate kinase 2/3, Pyruvate kinase M1/M2, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle, Pyruvate kinase muscle isozyme, THBP1

    基因ID

    5315

    NCBI登录号

    NP_001193725

    UniProt

    P14618

    途径

    Warburg Effect
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