PKM2 抗体
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北京 101111
Quick Overview for PKM2 抗体 (ABIN372199)
抗原
See all PKM2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody recognizes M1 and M2 Isoforms of Pyruvate Kinase (Rabbit Muscle).
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纯化方法
- IgG Fractionation.
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免疫原
- Pyruvate kinase purified from Rabbit muscle.
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亚型
- IgG
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应用备注
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Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western Blot: 1/500-1/2000. Immunoprecipitation. ELISA: 1/4000-1/20000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 10.0 mg/mL
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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别名
- PKM2
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背景
- PKM2 (pyruvate kinase, muscle) catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. It has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.Synonyms: CTHBP, Cytosolic thyroid hormone-binding protein, M2-PK, OIP-3, OIP3, Opa-interacting protein 3, PK2, PK3, PKM, Pyruvate kinase 2/3, Pyruvate kinase M1/M2, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle, Pyruvate kinase muscle isozyme, THBP1
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基因ID
- 5315
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NCBI登录号
- NP_001193725
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UniProt
- P14618
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途径
- Warburg Effect
抗原
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