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Retinoic Acid Receptor beta 抗体 (N-Term)

RARB 适用: 人, 小鼠, 大鼠, 犬, 豚鼠 WB 宿主: 小鼠 Monoclonal 336 unconjugated
产品编号 ABIN371838
发货至: 中国
  • 抗原 See all Retinoic Acid Receptor beta (RARB) 抗体
    Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
    抗原表位
    • 15
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 78
    • 35
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 豚鼠
    宿主
    • 70
    • 8
    小鼠
    克隆类型
    • 72
    • 6
    单克隆
    标记
    • 40
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Retinoic Acid Receptor beta antibody is un-conjugated
    应用范围
    • 69
    • 42
    • 15
    • 13
    • 13
    • 10
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody is specific for the ~48k RAR-beta isotype.
    交叉反应 (详细)
    Species reactivity (expected):Canine (Dog), Guinea Pig, Mouse and Rat.
    Species reactivity (tested):Human.
    产品特性
    Synonyms: RAR-epsilon, HAP, NR1B2, Retinoic acid receptor beta, HBV-activated protein, Nuclearreceptor subfamily 1 group B member 2
    纯化方法
    Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.
    免疫原
    Peptide corresponding to amino acids from N-terminal region of human retinoic acidreceptor, beta-isotype. Remarks: The antigen is identical in both beta-1 and beta-2 isoforms.
    克隆位点
    336
    亚型
    IgG1
    Top Product
    Discover our top product RARB Primary Antibody
  • 应用备注
    Western Blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
    别名
    RAR-beta / RARB (RARB 产品)
    别名
    RARB antibody, nRARs antibody, HAP antibody, NR1B2 antibody, RRB2 antibody, A830025K23 antibody, Hap antibody, Nr1b2 antibody, RARbeta2 antibody, RARBETA antibody, retinoic acid receptor beta antibody, retinoic acid receptor, beta antibody, RARB antibody, Rarb antibody
    背景
    Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: HAP, HBV-activated protein, NR1B2, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon, Retinoic acid receptor beta
    基因ID
    5915
    UniProt
    P10826
    途径
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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