Retinoic Acid Receptor beta 抗体 (N-Term)
Quick Overview for Retinoic Acid Receptor beta 抗体 (N-Term) (ABIN371838)
抗原
See all Retinoic Acid Receptor beta (RARB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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特异性
- This antibody is specific for the ~48k RAR-beta isotype.
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交叉反应 (详细)
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Species reactivity (expected):Canine (Dog), Guinea Pig, Mouse and Rat.
Species reactivity (tested):Human. -
产品特性
- Synonyms: RAR-epsilon, HAP, NR1B2, Retinoic acid receptor beta, HBV-activated protein, Nuclearreceptor subfamily 1 group B member 2
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纯化方法
- Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.
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免疫原
- Peptide corresponding to amino acids from N-terminal region of human retinoic acidreceptor, beta-isotype. Remarks: The antigen is identical in both beta-1 and beta-2 isoforms.
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亚型
- IgG1
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应用备注
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Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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储存条件
- -20 °C
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储存方法
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Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
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别名
- RAR-beta / RARB
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背景
- Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: HAP, HBV-activated protein, NR1B2, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon, Retinoic acid receptor beta
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基因ID
- 5915
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UniProt
- P10826
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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